Protein Overview: SGPL1_RAT

General Information:
Name(s) found:	SGPL1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|37999349\|sp\|Q8CHN6.1\|SGPL1_RAT RecName: Full=Sphingosine-1-phosphate lyase 1; Short=SP-lyase; Short=SPL; AltName: Full=Sphingosine-1-phosphate aldolase [NCBI NR] gi\|27465561\|ref\|NP_775139.1\| sphingosine-1-phosphate lyase 1 [Rattus norvegicus] [NCBI NR] gi\|24412855\|emb\|CAD55407.1\| sphingosine-1-phosphate lyase [Rattus norvegicus] [NCBI NR] Sphingosine-1-phosphate lyase 1 OS=Rattus norvegicus GN=Sgpl1 PE=2 SV=1 [Swiss-Prot] (Q8CHN6) Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (SPL) (Sphingosine-1-phosphate aldolase) [Swiss-Prot] Ensembl_locations(Chr-bp):20-43667848;20-43667848 Sphingosine-1-phosphate lyase [hmr_yeast5_DM3-1_pombe.fasta] sphingosine-1-phosphate lyase 1 [HMR_022704-rand.fasta] sphingosine-1-phosphate lyase 1 [Rattus norvegicus]gi\|24412855\|emb\|CAD55407.1\| sphingosine-1-phosphate lyase [Rattus norvegicus]gi\|37999349\|sp\|Q8CHN6\|SGP1_RAT Sphingosine-1-phosphate lyase 1 (SP-lyase) (SPL) (Sphingosine-1-phosphate aldolase) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Sphingosine-1-phosphate lyase 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Sphingosine-1-phosphate lyase 1 (SP-lyase) (SPL) (Sphingosine-1-phosphate aldolase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] sphingosine phosphate lyase 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] sphingosine-1-phosphate lyase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPHINGOSINE-1-PHOSPHATE LYASE 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] sphingosine-1-phosphate lyase 1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Sgpl1 Sphingosine-1-phosphate lyase 1 [rat-ipi-250309-contam.fasta] Sphingosine-1-phosphate lyase 1 OS=Rattus norvegicus GN=Sgpl1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	568 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [IEA] membrane [IEA] integral to membrane [IEA] endoplasmic reticulum [UNKNOWN][IEA]
Biological Process:	regulation of multicellular organism growth [UNKNOWN][IEA] estrogen metabolic process [UNKNOWN] spermatogenesis [UNKNOWN] hemopoiesis [UNKNOWN][IEA] post-embryonic development [UNKNOWN][IEA] palate development [UNKNOWN][IEA] platelet-derived growth factor receptor signaling pathway [UNKNOWN][IEA] vasculogenesis [UNKNOWN][IEA] ceramide metabolic process [UNKNOWN][ISS] female gonad development [UNKNOWN] skeletal system morphogenesis [UNKNOWN][IEA] face morphogenesis [UNKNOWN][IEA] luteinization [UNKNOWN] androgen metabolic process [UNKNOWN] kidney development [UNKNOWN][IEA] nitrogen compound metabolic process [UNKNOWN][IEA] lipid metabolic process [IEA] apoptosis [UNKNOWN][ISS] carboxylic acid metabolic process [IEA] fibroblast migration [UNKNOWN][IEA] Leydig cell differentiation [UNKNOWN]
Molecular Function:	pyridoxal phosphate binding [IEA] catalytic activity [IEA] lyase activity [IEA] sphinganine-1-phosphate aldolase activity [IEA] carboxy-lyase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSTDLLKLK DFEPYLEILE AYSTKAKNYV NGYCTKYEPW QLIAGSVLCT LLVVWVYELI  60
   61 FQPESLWSRF KNKLFRLIRK MPFIGRKIQQ QLTKAKKDLV KNMPFLKLDK DYVKTLPAQG 120
  121 LSTAEVLERL KEYSSMDVFW QEGKASGAVY SGEPKLTELL VQAYGEFTWS NPLHPDIFPG 180
  181 LRKLEAEIVR MTCSLFNGGP DSCGCVTSGG TESILMACKA YRDLALEKGI KTPEIVAPES 240
  241 AHAAFDKAAH YFGMKIVRVA QKKNMEVDVR AMKRAISRNT AMLVCSAPQF PHGVIDPIPE 300
  301 VAKLAVKYKI PFHVDACLGG FLIVFMEKAG YPLEKPFDFR VKGVTSISAD THKYGYAPKG 360
  361 SSVVMYSNEK YRKYQFFVDA DWQGGIYASP SIAGSRPGGI IAACWAALMH FGENGYVEAT 420
  421 KQIIKTARFL KSELENIKNI FILGDPQLSV IALGSNDFDI YRLSNMMSAK GWNFNYLQFP 480
  481 RSIHFCITLV HTRKRVAIQF LKDIRESVTQ IMKNPKAKTT GMGAIYGMAQ ATIDRKMVAE 540
  541 ISSVFLDSLY STDPVTQGNQ MNGSPKPR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: SGPL1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: