Protein Overview: LIF_RAT

General Information:
Name(s) found:	LIF_RAT [Swiss-Prot]
Description(s) found: Found 15 descriptions. SHOW ALL	Leukemia inhibitory factor OS=Rattus norvegicus GN=Lif PE=2 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	202 amino acids
Gene Ontology:
Cellular Component:	extracellular space [IEA] extracellular region [IEA]
Biological Process:	lung lobe morphogenesis [UNKNOWN] positive regulation of tyrosine phosphorylation of Stat3 protein [UNKNOWN][IEA] negative regulation of cell proliferation [UNKNOWN] positive regulation of cell proliferation [UNKNOWN][IEA] lung vasculature development [UNKNOWN] decidualization [UNKNOWN][IEA] positive regulation of astrocyte differentiation [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] lung alveolus development [UNKNOWN] immune response [IEA] regulation of cell differentiation [UNKNOWN][IEA] positive regulation of macrophage differentiation [UNKNOWN][IEA] leukemia inhibitory factor signaling pathway [UNKNOWN][IEA] trophoblast giant cell differentiation [UNKNOWN][IEA] spongiotrophoblast differentiation [UNKNOWN][IEA] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] positive regulation of peptidyl-tyrosine phosphorylation [UNKNOWN][IEA] lung development [UNKNOWN] positive regulation of peptidyl-serine phosphorylation [UNKNOWN][IEA] tyrosine phosphorylation of Stat3 protein [UNKNOWN] stem cell maintenance [UNKNOWN][IEA] maternal process involved in female pregnancy [UNKNOWN][IEA] positive regulation of MAPKKK cascade [UNKNOWN][IEA] muscle organ morphogenesis [UNKNOWN][IEA] neuron development [UNKNOWN][IEA] negative regulation of meiosis [UNKNOWN][IEA] embryo implantation [UNKNOWN][IEA] negative regulation of hormone secretion [UNKNOWN][IEA] blood vessel remodeling [UNKNOWN] negative regulation of ERK1 and ERK2 cascade [UNKNOWN] organ regeneration [IMP]
Molecular Function:	growth factor activity [UNKNOWN][IEA] cytokine activity [UNKNOWN][IEA] receptor binding [UNKNOWN] leukemia inhibitory factor receptor binding [UNKNOWN][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVLAAGIVP LLLILHWKHG AGSPLPITPV NATCAIRHPC HGNLMNQIKS QLAQLNGSAN  60
   61 ALFISYYTAQ GEPFPNNVDK LCAPNMTDFP PFHANGTEKT KLVELYRMVT YLGASLTNIT 120
  121 WDQKNLNPTA VSLQIKLNAT TDVMRGLLSS VLCRLCNKYH VGHVDVPCVP DNSSKEAFQR 180
  181 KKLGCQLLGT YKQVISVLAQ AF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: LIF_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: