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Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. The process by which an organism retains a population of meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. The process whereby a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). The process by which an organism retains a population of stem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features. Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation. The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. The process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. Any process involved in preventing uncommitted germ-line stem cells from differentiating as another cell type.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: stem cell maintenance
Acc: GO:0019827
Aspect: Biological Process
Desc: The process by which an organism retains a population of stem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
Synonyms:
  • maintenance of pluripotency
Proteins in PDR annotated with:
   This term: 43 [Search]
   Term or descendants: 167 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0019827 - stem cell maintenance (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle