Protein Overview: GSK3A_RAT

General Information:
Name(s) found:	GSK3A_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8393496\|ref\|NP_059040.1\| glycogen synthase kinase 3 alpha [Rattus norvegicus] [NCBI NR] pir\|\|TVRTKA protein kinase (EC 2.7.1.37) GSK-3-alpha - rat [NCBI NR] gi\|56332\|emb\|CAA37518.1\| unnamed protein product [Rattus norvegicus] [NCBI NR] gi\|149056606\|gb\|EDM08037.1\| rCG53745 [Rattus norvegicus] [NCBI NR] gi\|125373\|sp\|P18265.1\|GSK3A_RAT RecName: Full=Glycogen synthase kinase-3 alpha; Short=GSK-3 alpha; AltName: Full=Factor A; Short=FA [NCBI NR] (P18265) Glycogen synthase kinase-3 alpha (EC 2.7.1.37) (GSK-3 alpha) (Factor A) (FA) [Swiss-Prot] Glycogen synthase kinase-3 alpha OS=Rattus norvegicus GN=Gsk3a PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):1-77636555 Glycogen synthase kinase-3 alpha [hmr_yeast5_DM3-1_pombe.fasta] glycogen synthase kinase 3 alpha [HMR_022704-rand.fasta] glycogen synthase kinase 3 alpha [Rattus norvegicus]gi\|56332\|emb\|CAA37518.1\| unnamed protein product [Rattus norvegicus]gi\|125373\|sp\|P18265\|KG3A_RAT Glycogen synthase kinase-3 alpha (GSK-3 alpha) (Factor A) (FA)gi\|66743\|pir\|\|TVRTKA protein kinase (EC 2 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Glycogen synthase kinase-3 alpha [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_017344) glycogen synthase kinase 3 alpha [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] glycogen synthase kinase 3 alpha [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Glycogen synthase kinase-3 alpha (GSK-3 alpha) (Factor A) (FA) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG53745 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 GLYCOGEN SYNTHASE KINASE-3 ALPHA [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Gsk3a Glycogen synthase kinase-3 alpha [rat-ipi-250309-contam.fasta] Glycogen synthase kinase-3 alpha OS=Rattus norvegicus GN=Gsk3a [011711_HMR.fasta] Isoform of P18265, Glycogen synthase kinase-3 alpha OS=Rattus norvegicus GN=Gsk3a PE=1 SV=3 [RAT.fasta.20160308]
Organism:	Rattus norvegicus
Length:	483 amino acids
Gene Ontology:
Cellular Component:	cytosol [UNKNOWN]
Biological Process:	cellular response to insulin stimulus [UNKNOWN] signal transduction [NAS] negative regulation of glucose import [UNKNOWN][IEA] positive regulation of peptidyl-threonine phosphorylation [UNKNOWN] protein amino acid phosphorylation [UNKNOWN][IDA] cell migration [UNKNOWN] negative regulation of insulin receptor signaling pathway [UNKNOWN][IEA] positive regulation of peptidyl-serine phosphorylation [UNKNOWN] negative regulation of transferase activity [UNKNOWN][IEA]
Molecular Function:	nucleotide binding [IEA] tau-protein kinase activity [IEA] ATP binding [IEA] protein binding [UNKNOWN][IEA] protein kinase A catalytic subunit binding [UNKNOWN][IPI] protein kinase activity [UNKNOWN] protein serine/threonine kinase activity [UNKNOWN][IDA] glycogen synthase kinase 3 activity [UNKNOWN][IDA][NAS] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGGGPSGGG PGGSGRARTS SFAEPGGGGG GGGGGPGGSA SGPGGTGGGK ASVGAMGGGV  60
   61 GASSSGGGPS GSGGGGSGGP GAGTSFPPPG VKLGRDSGKV TTVVATLGQG PERSQEVAYT 120
  121 DIKVIGNGSF GVVYQARLAE TRELVAIKKV LQDKRFKNRE LQIMRKLDHC NIVRLRYFFY 180
  181 SSGEKKDELY LNLVLEYVPE TVYRVARHFT KAKLIIPIIY VKVYMYQLFR SLAYIHSQGV 240
  241 CHRDIKPQNL LVDPDTAVLK LCDFGSAKQL VRGEPNVSYI CSRYYRAPEL IFGATDYTSS 300
  301 IDVWSAGCVL AELLLGQPIF PGDSGVDQLV EIIKVLGTPT REQIREMNPN YTEFKFPQIK 360
  361 AHPWTKVFKS RTPPEAIALC SSLLEYTPSS RLSPLEACAH SFFDELRSLG TQLPNNRPLP 420
  421 PLFNFSPGEL SIQPSLNAIL IPPHLRSPSG PATLTSSSQA LTETQTGQDW QAPDATPTLT 480
  481 NSS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: GSK3A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: