General Information: |
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Name(s) found: |
HES1_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 281 amino acids |
Gene Ontology: |
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Cellular Component: |
nucleus
[UNKNOWN][IEA]
cytoplasm [UNKNOWN] |
Biological Process: |
neural tube development
[UNKNOWN]
negative regulation of auditory receptor cell differentiation [UNKNOWN] positive regulation of cell proliferation [UNKNOWN] regulation of timing of neuron differentiation [UNKNOWN] midbrain-hindbrain boundary morphogenesis [UNKNOWN] negative regulation of neuron differentiation [UNKNOWN] cell adhesion [UNKNOWN] oculomotor nerve development [UNKNOWN] trochlear nerve development [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN] hindbrain morphogenesis [UNKNOWN] negative regulation of transcription from RNA polymerase II promoter [UNKNOWN][IDA] midbrain development [UNKNOWN] in utero embryonic development [UNKNOWN] negative regulation of cell differentiation [UNKNOWN] liver development [UNKNOWN] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] lung development [UNKNOWN] auditory receptor cell fate determination [UNKNOWN] regulation of transcription, DNA-dependent [IEA] smoothened signaling pathway [UNKNOWN] cell maturation [UNKNOWN] cell morphogenesis involved in neuron differentiation [UNKNOWN] negative regulation of stomach neuroendocrine cell differentiation [UNKNOWN] pituitary gland development [UNKNOWN] regulation of timing of cell differentiation [UNKNOWN] Notch signaling pathway [UNKNOWN] auditory receptor cell differentiation [UNKNOWN] cell fate commitment [UNKNOWN] regulation of neurogenesis [UNKNOWN] |
Molecular Function: |
DNA binding
[UNKNOWN][IEA]
protein binding [IPI] transcription repressor activity [UNKNOWN][IDA][TAS] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MPADIMEKNS SSPVAATPAS VNTTPDKPKT ASEHRKSSKP IMEKRRRARI NESLSQLKTL 60 61 ILDALKKDSS RHSKLEKADI LEMTVKHLRN LQRAQMTAAL STDPSVLGKY RAGFSECMNE 120 121 VTRFLSTCEG VNTEVRTRLL GHLANCMTQI NAMTYPGQAH PALQAPPPPP PSGPGGPQHA 180 181 PFAPPPPLVP IPGGAAPPPG SAPCKLGSQA GEAAKVFGGF QVVPAPDGQF AFLIPNGAFA 240 241 HSGPVIPVYT SNSGTSVGPN AVSPSSGSSL TADSMWRPWR N |
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.97 |
Source: Reynolds et al. (2008)