Protein Overview: HES1_RAT

General Information:
Name(s) found:	HES1_RAT [Swiss-Prot]
Description(s) found: Found 21 descriptions. SHOW ALL	Transcription factor HES-1 OS=Rattus norvegicus GN=Hes1 PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	281 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA] cytoplasm [UNKNOWN]
Biological Process:	neural tube development [UNKNOWN] negative regulation of auditory receptor cell differentiation [UNKNOWN] positive regulation of cell proliferation [UNKNOWN] regulation of timing of neuron differentiation [UNKNOWN] midbrain-hindbrain boundary morphogenesis [UNKNOWN] negative regulation of neuron differentiation [UNKNOWN] cell adhesion [UNKNOWN] oculomotor nerve development [UNKNOWN] trochlear nerve development [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN] hindbrain morphogenesis [UNKNOWN] negative regulation of transcription from RNA polymerase II promoter [UNKNOWN][IDA] midbrain development [UNKNOWN] in utero embryonic development [UNKNOWN] negative regulation of cell differentiation [UNKNOWN] liver development [UNKNOWN] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] lung development [UNKNOWN] auditory receptor cell fate determination [UNKNOWN] regulation of transcription, DNA-dependent [IEA] smoothened signaling pathway [UNKNOWN] cell maturation [UNKNOWN] cell morphogenesis involved in neuron differentiation [UNKNOWN] negative regulation of stomach neuroendocrine cell differentiation [UNKNOWN] pituitary gland development [UNKNOWN] regulation of timing of cell differentiation [UNKNOWN] Notch signaling pathway [UNKNOWN] auditory receptor cell differentiation [UNKNOWN] cell fate commitment [UNKNOWN] regulation of neurogenesis [UNKNOWN]
Molecular Function:	DNA binding [UNKNOWN][IEA] protein binding [IPI] transcription repressor activity [UNKNOWN][IDA][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPADIMEKNS SSPVAATPAS VNTTPDKPKT ASEHRKSSKP IMEKRRRARI NESLSQLKTL  60
   61 ILDALKKDSS RHSKLEKADI LEMTVKHLRN LQRAQMTAAL STDPSVLGKY RAGFSECMNE 120
  121 VTRFLSTCEG VNTEVRTRLL GHLANCMTQI NAMTYPGQAH PALQAPPPPP PSGPGGPQHA 180
  181 PFAPPPPLVP IPGGAAPPPG SAPCKLGSQA GEAAKVFGGF QVVPAPDGQF AFLIPNGAFA 240
  241 HSGPVIPVYT SNSGTSVGPN AVSPSSGSSL TADSMWRPWR N

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: HES1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: