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Protein Overview: MP2K5_MOUSE

General Information:
Name(s) found: MP2K5_MOUSE [Swiss-Prot]
Description(s) found:
Found 21 descriptions.
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  • Dual specificity mitogen-activated protein kinase kinase 5 OS=Mus musculus GN=Map2k5 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 448 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN]
    cytoplasm [IEA]
    spindle [IDA]
    cytosol [UNKNOWN]
    Biological Process: MAPKKK cascade [IMP]
    heart development [IMP]
    positive regulation of cell growth [UNKNOWN]
    BMK cascade [UNKNOWN]
    auxin biosynthetic process [IEA]
    protein amino acid phosphorylation [UNKNOWN]
    positive regulation of epithelial cell proliferation [UNKNOWN]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [UNKNOWN]
    protein tyrosine kinase activity [IEA]
    protein binding [IPI]
    metal ion binding [IEA]
    protein kinase activity [UNKNOWN]
    protein serine/threonine kinase activity [IEA]
    transferase activity [IEA]
    kinase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLWLALGPFC AMENQVLVIR IKIPNSGAVD WTVHSGPQLL FRDVLDVIGQ VLPEATTTAF  60
   61 EYEDEDGDRI TVRSDEEMKA MLSYYYSTVM EQQVNGQLIE PLQIFPRACK PPGERNIHGL 120
  121 KVNTRAGPSQ HTSPVVSDSL PSNSLKKSSA ELRKILANGQ MNEQDIRYRD TLGHGNGGTV 180
  181 YKAHHVPSGK ILAVKVILLD ITLELQKQIM SELEILYKCD SSYIIGFYGA FFVENRISIC 240
  241 TEFMDGGSLD VYRKIPEHVL GRIAVAVVKG LTYLWSLKIL HRDVKPSNML VNTGGQVKLC 300
  301 DFGVSTQLVN SIAKTYVGTN AYMAPERISG EQYGIHSDVW SLGISFMELA LGRFPYPQIQ 360
  361 KNQGSLMPLQ LLQCIVDEDS PVLPLGEFSE PFVHFITQCM RKQPKERPAP EELMGHPFIV 420
  421 QFNDGNSTVV SMWVCRALEE RRSQQGPP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle