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Protein Overview: ORC6_MOUSE

General Information:
Name(s) found: ORC6_MOUSE [Swiss-Prot]
Description(s) found:
Found 20 descriptions.
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  • Origin recognition complex subunit 6 OS=Mus musculus GN=Orc6 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 262 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    nuclear origin of replication recognition complex [IEA]
    cellular_component [ND]
    Biological Process: biological_process [ND]
    DNA replication [IEA]
    Molecular Function: DNA binding [IEA]
    molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESELVRRLA PRLGLAEPSV LRKAEEFLRL SKVKCVSLSA RSSETSNAVI CLDLAASCRK  60
   61 CPLDRAYLIR LSGLNKMMYQ SCLKSFECLL GLNSNVGIRD LAVQFSCTEA VNLAAEILQS 120
  121 YKSGLPETQR ADLDLSRPLF TTAALLSACK ILKIKVDKTK MITTSGVKKA ILDRLCKQLE 180
  181 KIGQQINRDS ADLARPALKR KKPEFSPTLK KKEPGLEPPA KEIEVIETLH KLPKDEDLTQ 240
  241 DYEEWKRKIL ENAAKAQTAT AE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..262] FFAS03 1.39 NMR STUDIES OF HUMAN GENERAL TRANSCRIPTION FACTOR TFIIB: DYNAMICS AND INTERACTION WITH VP16 ACTIVATION DOMAIN, 20 STRUCTURES

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  2.75688185850223 bayes_pls_golite062009
  • binding
    		•  2.37916921859542 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  2.37399236069363 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.06743451505655 bayes_pls_golite062009
  • DNA binding
    		•  1.95321993038755 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.41828738664896 bayes_pls_golite062009
  • cyclin-dependent protein kinase regulator activity
    		•  1.41497909264171 bayes_pls_golite062009
  • protein binding
    		•  1.37207701115974 bayes_pls_golite062009
  • transcription factor activity
    		•  1.22628491144894 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  1.21941169140389 bayes_pls_golite062009
  • kinase regulator activity
    		•  1.18590233040331 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.962670695182671 bayes_pls_golite062009
  • transcription factor binding
    		•  0.655253705928308 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.461517963237846 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.0843751392410543 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0606514459376675 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle