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Protein Overview: PLCD1_MOUSE, PID...

General Information:
Name(s) found: PLCD1_MOUSE [Swiss-Prot]
PID1_MOUSE [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 OS=Mus musculus GN=Plcd1 PE=2 SV=1 [Swiss-Prot]
  • (Q8R3B1) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III) [Swiss-Prot]
    • Organism: Mus musculus
    Length: 756 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [UNKNOWN]
    nucleus [UNKNOWN]
    mitochondrial membrane [UNKNOWN]
    cytoplasm [UNKNOWN]
    membrane raft [UNKNOWN]
    cytosol [UNKNOWN][IDA]
    Biological Process: G-protein coupled receptor protein signaling pathway [UNKNOWN]
    signal transduction [IEA]
    response to peptide hormone stimulus [UNKNOWN]
    regulation of cell proliferation [IGI]
    intracellular signaling pathway [IEA]
    labyrinthine layer blood vessel development [IGI]
    angiogenesis [IGI]
    elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger [UNKNOWN]
    response to calcium ion [UNKNOWN]
    lipid catabolic process [IEA]
    lipid metabolic process [IEA]
    positive regulation of norepinephrine secretion [UNKNOWN]
    positive regulation of inositol trisphosphate biosynthetic process [UNKNOWN]
    Molecular Function: phosphoinositide phospholipase C activity [UNKNOWN]
    phosphatidylinositol-4,5-bisphosphate binding [UNKNOWN]
    metal ion binding [IEA]
    calcium ion binding [UNKNOWN]
    phospholipase C activity [IEA]
    phospholipid binding [UNKNOWN]
    phosphoric diester hydrolase activity [IEA]
    signal transducer activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSGRDFLTL HGLQDDPDLQ ALLKGSQLLK VKSSSWRRER FYKLQEDCKT IWQESRKVMR  60
   61 SPESQLFSIE DIQEVRMGHR TEGLEKFARD IPEDRCFSIV FKDQRNTLDL IAPSPADVQH 120
  121 WVQGLRKIID RSGSMDQRQK LQHWIHSCLR KADKNKDNKM NFKEVKDFLK ELNVQVDDSY 180
  181 ARKIFRECDH SQTDSLEDEE IETFYRMLTQ RVEIDRAFAE AAGSAETLSV EKLVTFLQHQ 240
  241 QREEEAGPAL ALSLIERYEP SETAKAQRQM TKDGFLMYLL SADGNAFSLA HRRVYQDMNQ 300
  301 PLSHYLVSSS HNTYLLEDQL TGPSSTEAYI RALCKGCRCL ELDCWDGPNQ EPIIYHGYTF 360
  361 TSKILFCDVL RAIRDYAFKA SPYPVILSLE NHCSLEQQRV MAHHLRAILG PMLLDQPLDG 420
  421 VTTSLPSPEQ LKEKILLKGK KLGGLLPAGG ENGPEATDVS DEDEAAEMED EAVRSQVQHK 480
  481 PKEDKLKLVP ELSDMVIYCK SVHFGGFSSP STSGQAFYEM ASFSESRALR LLQESGNSFV 540
  541 RHNVGHLSRI YPAGWRTDSS NYSPVEMWNG GCQIVALNFQ TPGPEMDVYL GCFQDNGGCG 600
  601 YVLKPAFLRD PDTTFNSRAL TQGPWWAPKK LRVWIISGQQ LPKVNKNKNS IVDPKVIVEI 660
  661 HGVGQDVASR QTAVITNNGF NPRWDTEFEF VVAVPDLALV RFMVEDYDSS SKNDFIGQST 720
  721 IPWNSLKQGY RHVHLLSKNG DLHPSATLFV KISIQD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle