Protein Overview: ACV1B_MOUSE

General Information:
Name(s) found:	ACV1B_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|840813\|emb\|CAA83483.1\| activin type IB receptor [Mus musculus] [NCBI NR] gi\|74192086\|dbj\|BAE34258.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|6680630\|ref\|NP_031421.1\| activin A receptor, type 1B [Mus musculus] [NCBI NR] gi\|59799088\|sp\|Q61271.1\|ACV1B_MOUSE RecName: Full=Activin receptor type-1B; AltName: Full=ACTR-IB; AltName: Full=Serine/threonine-protein kinase receptor R2; Short=SKR2; AltName: Full=Activin receptor-like kinase 4; Short=ALK-4; Flags: Precursor [NCBI NR] gi\|148878276\|gb\|AAI45778.1\| Activin A receptor, type 1B [Mus musculus] [NCBI NR] gi\|148877577\|gb\|AAI45776.1\| Activin A receptor, type 1B [Mus musculus] [NCBI NR] (Q61271) Serine/threonine-protein kinase receptor R2 precursor (EC 2.7.1.37) (SKR2) (Activin type IB receptor) (ACTR-IB) [Swiss-Prot] Activin receptor type-1B OS=Mus musculus GN=Acvr1b PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):15-101613530 Activin type IB receptor precursor [hmr_yeast5_DM3-1_pombe.fasta] activin A receptor, type 1B [HMR_022704-rand.fasta] Serine/threonine-protein kinase receptor R2 precursor [ipi.MOUSE.v3.06.fasta] activin A receptor, type 1B [Mus musculus]gi\|840813\|emb\|CAA83483.1\| activin type IB receptor [Mus musculus] [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Activin receptor type 1B precursor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_007395) activin A receptor, type 1B [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] activin A receptor, type 1B [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Tax_Id=10090 Serine/threonine-protein kinase receptor R2 precursor [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] Activin receptor type-1B precursor (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Activin A receptor, type 1B [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] activin type IB receptor [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 SERINE/THREONINE-PROTEIN KINASE RECEPTOR R2 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Acvr1b Activin receptor type-1B [mouse-ipi-250309-contam.fasta] activin A receptor, type 1B precursor [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Acvr1b Activin receptor type-1B precursor [ipi.MOUSE_jw_12may08.contam.fasta] Activin receptor type 1B precursor (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) [nr-271106-contam.fasta] Tax_Id=10090 Gene_Symbol=Acvr1b Activin receptor type 1B precursor [zeeyong.fasta] Tax_Id=10090 Gene_Symbol=Acvr1b Activin receptor type-1B precursor ENSMUSG00000000532 IPI00119012 [IPIxENS.MOUSE_plus_REVERSE.fasta] activin receptor type-1B precursor [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00119012.1\|SWISS-PROT:Q61271\|TREMBL:Q3TZF1\|ENSEMBL:ENSMUSP00000000544\|REFSEQ:NP_031421 Tax_Id=10090 Gene_Symbol=Acvr1b Activin receptor type-1B [ipi.MOUSE.fasta.20090209] Activin receptor type-1B OS=Mus musculus GN=Acvr1b [011711_HMR.fasta] sp\|Q61271\|ACV1B_MOUSE Activin receptor type-1B OS=Mus musculus GN=Acvr1b PE=1 SV=1 [uniprot.sptr.mouse.20130102] tr\|Q3TZF1\|Q3TZF1_MOUSE Activin A receptor, type 1B OS=Mus musculus GN=Acvr1b PE=2 SV=1 [uniprot.sptr.mouse.20130102] Activin A receptor, type 1B OS=Mus musculus GN=Acvr1b PE=2 SV=1 [mouse-uniprot-290313-contam.fasta] Isoform of Q61271, Receptor protein serine/threonine kinase OS=Mus musculus GN=Acvr1b PE=1 SV=1 [MOUSE.fasta.20160308]
Organism:	Mus musculus
Length:	505 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [TAS] activin receptor complex [UNKNOWN] membrane [IEA] integral to membrane [IEA]
Biological Process:	embryonic development [IMP] hair follicle development [IMP] in utero embryonic development [IMP] mesoderm development [UNKNOWN] auxin biosynthetic process [IEA] cell surface receptor linked signaling pathway [TAS] protein amino acid phosphorylation [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN] peptidyl-threonine phosphorylation [IDA] positive regulation of pathway-restricted SMAD protein phosphorylation [UNKNOWN]
Molecular Function:	transforming growth factor beta receptor activity [IEA] protein kinase activity [IEA] receptor activity [IEA] protein serine/threonine kinase activity [IDA] transmembrane receptor protein serine/threonine kinase activity [TAS] nucleotide binding [IEA] ATP binding [IEA] receptor signaling protein serine/threonine kinase activity [UNKNOWN] protein binding [IPI] activin binding [IPI] SMAD binding [UNKNOWN] metal ion binding [IEA] activin receptor activity, type I [UNKNOWN] transferase activity [IEA] kinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAESAGASSF FPLVVLLLAG SGGSGPRGIQ ALLCACTSCL QTNYTCETDG ACMVSIFNLD  60
   61 GVEHHVRTCI PKVELVPAGK PFYCLSSEDL RNTHCCYIDF CNKIDLRVPS GHLKEPAHPS 120
  121 MWGPVELVGI IAGPVFLLFL IIIIVFLVIN YHQRVYHNRQ RLDMEDPSCE MCLSKDKTLQ 180
  181 DLVYDLSTSG SGSGLPLFVQ RTVARTIVLQ EIIGKGRFGE VWRGRWRGGD VAVKIFSSRE 240
  241 ERSWFREAEI YQTVMLRHEN ILGFIAADNK DNGTWTQLWL VSDYHEHGSL FDYLNRYTVT 300
  301 IEGMIKLALS AASGLAHLHM EIVGTQGKPG IAHRDLKSKN ILVKKNGMCA IADLGLAVRH 360
  361 DAVTDTIDIA PNQRVGTKRY MAPEVLDETI NMKHFDSFKC ADIYALGLVY WEIARRCNSG 420
  421 GVHEDYQLPY YDLVPSDPSI EEMRKVVCDQ KLRPNVPNWW QSYEALRVMG KMMRECWYAN 480
  481 GAARLTALRI KKTLSQLSVQ EDVKI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ACV1B_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: