Protein Overview: CXA1_MOUSE

General Information:
Name(s) found:	CXA1_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|74216958\|dbj\|BAE26592.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|74139244\|dbj\|BAE38502.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|71059983\|emb\|CAJ18535.1\| Npm1 [Mus musculus] [NCBI NR] gi\|6753992\|ref\|NP_034418.1\| gap junction protein, alpha 1 [Mus musculus] [NCBI NR] gi\|50523\|emb\|CAA44640.1\| Connexin 43 [Mus musculus] [NCBI NR] gi\|50510\|emb\|CAA43778.1\| connexin 43 [Mus musculus] [NCBI NR] gi\|26331852\|dbj\|BAC29656.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|192679\|gb\|AAA37444.1\| connexin 43 [Mus musculus] [NCBI NR] gi\|148673161\|gb\|EDL05108.1\| mCG10836 [Mus musculus] [NCBI NR] gi\|13905196\|gb\|AAH06894.1\| Gap junction protein, alpha 1 [Mus musculus] [NCBI NR] gi\|117707\|sp\|P23242.2\|CXA1_MOUSE RecName: Full=Gap junction alpha-1 protein; AltName: Full=Connexin-43; Short=Cx43; AltName: Full=Gap junction 43 kDa heart protein [NCBI NR] pir\|\|A39802 gap junction protein Cx43 - mouse [NCBI NR] Gap junction alpha-1 protein OS=Mus musculus GN=Gja1 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):10-56341517 gap junction membrane channel protein alpha 1 [hmr_yeast5_DM3-1_pombe.fasta] gap junction membrane channel protein alpha 1; connexin 43; alpha 1 connexin [HMR_022704-rand.fasta] gap junction membrane channel protein alpha 1 [Mus musculus]gi\|13905196\|gb\|AAH06894.1\| Gap junction membrane channel protein alpha 1 [Mus musculus]gi\|117707\|sp\|P23242\|CXA1_MOUSE Gap junction alpha-1 protein (Connexin 43) (Cx43) (Gap junction 43 kDa hear [nrdb_11152004_Chlamydomonas] (NM_010288) gap junction membrane channel protein alpha 1; connexin 43; alpha 1 connexin [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] gap junction membrane channel protein alpha 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] gap junction protein, alpha 1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Gap junction protein, alpha 1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] mCG10836 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Npm1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Connexin 43 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] connexin 43 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] connexin 43 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Gap junction membrane channel protein alpha 1 [Mus musculus] [nr-271106-contam.fasta] gap junction alpha-1 protein [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] Gap junction alpha-1 protein OS=Mus musculus GN=Gja1 [122011_mus.fasta] Tax_Id=10090 Gene_Symbol=Gja1 Gap junction alpha-1 protein [EBI-IPI_mouse_2_08-18-2011_reversed.fasta] sp\|P23242\|CXA1_MOUSE Gap junction alpha-1 protein OS=Mus musculus GN=Gja1 PE=1 SV=2 [uniprot.sptr.mouse.20130102] Gap junction protein OS=Mus musculus GN=Gja1 PE=2 SV=1 [UniProt_mouse_01-27-2011_reversed.fasta]
Organism:	Mus musculus
Length:	382 amino acids
Gene Ontology:
Cellular Component:	late endosome [UNKNOWN] endoplasmic reticulum [UNKNOWN] multivesicular body [UNKNOWN] mitochondrial outer membrane [UNKNOWN] plasma membrane [UNKNOWN][IDA] lysosome [UNKNOWN] gap junction [UNKNOWN][IDA] early endosome [UNKNOWN] connexon complex [UNKNOWN] cell-cell junction [IDA] cytoplasm [UNKNOWN] fascia adherens [UNKNOWN] membrane [IEA] integral to membrane [IEA] cytosol [IDA] cell junction [IDA]
Biological Process:	cell communication [UNKNOWN] negative regulation of cell proliferation [UNKNOWN] neuron projection morphogenesis [UNKNOWN] blood vessel morphogenesis [IMP] adult heart development [IMP] positive regulation of striated muscle tissue development [IMP] skeletal muscle tissue regeneration [IDA] heart development [IMP] neuron migration [IMP] in utero embryonic development [IMP] apoptosis [UNKNOWN][IMP] heart looping [IMP] regulation of calcium ion transport [UNKNOWN] ATP transport [UNKNOWN] vascular transport [UNKNOWN] epithelial cell maturation [IMP] limb bud formation [IMP] cell-cell signaling [UNKNOWN][IDA] regulation of heart contraction [IMP] positive regulation of protein catabolic process [UNKNOWN] response to pH [UNKNOWN] embryonic heart tube development [IMP] negative regulation of gene expression [IMP] positive regulation of gene expression [IMP] protein oligomerization [UNKNOWN]
Molecular Function:	protein domain specific binding [UNKNOWN] transmembrane transporter activity [IEA] PDZ domain binding [UNKNOWN] SH3 domain binding [UNKNOWN] gap junction channel activity [UNKNOWN][IDA] receptor binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDWSALGKL LDKVQAYSTA GGKVWLSVLF IFRILLLGTA VESAWGDEQS AFRCNTQQPG  60
   61 CENVCYDKSF PISHVRFWVL QIIFVSVPTL LYLAHVFYVM RKEEKLNKKE EELKVAQTDG 120
  121 VNVEMHLKQI EIKKFKYGIE EHGKVKMRGG LLRTYIISIL FKSVFEVAFL LIQWYIYGFS 180
  181 LSAVYTCKRD PCPHQVDCFL SRPTEKTIFI IFMLVVSLVS LALNIIELFY VFFKGVKDRV 240
  241 KGRSDPYHAT TGPLSPSKDC GSPKYAYFNG CSSPTAPLSP MSPPGYKLVT GDRNNSSCRN 300
  301 YNKQASEQNW ANYSAEQNRM GQAGSTISNS HAQPFDFPDD SQNAKKVAAG HELQPLAIVD 360
  361 QRPSSRASSR ASSRPRPDDL EI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: CXA1_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: