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Protein Overview: ID2_MOUSE

General Information:
Name(s) found: ID2_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|8039784|sp|P41136.3|ID2_MOUSE RecName: Full=DNA-binding protein inhibitor ID-2; AltName: Full=Inhibitor of DNA binding 2 [NCBI NR]
  • gi|74226911|dbj|BAE27099.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74183322|dbj|BAE22577.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74144623|dbj|BAE27298.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|6754276|ref|NP_034626.1| inhibitor of DNA binding 2 [Mus musculus] [NCBI NR]
  • gi|3420741|gb|AAD05214.1| helix-loop-helix protein Id2 [Mus musculus] [NCBI NR]
  • gi|31565598|gb|AAH53699.1| Inhibitor of DNA binding 2 [Mus musculus] [NCBI NR]
  • gi|148705032|gb|EDL36979.1| inhibitor of DNA binding 2 [Mus musculus] [NCBI NR]
  • gi|13905248|gb|AAH06921.1| Inhibitor of DNA binding 2 [Mus musculus] [NCBI NR]
  • gi|12833755|dbj|BAB22651.1| unnamed protein product [Mus musculus] [NCBI NR]
  • DNA-binding protein inhibitor ID-2 OS=Mus musculus GN=Id2 PE=1 SV=3 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):12-19205602 DNA-binding protein inhibitor ID-2 [hmr_yeast5_DM3-1_pombe.fasta]
  • inhibitor of DNA binding 2; inhibitor of differentiation 2 [HMR_022704-rand.fasta]
  • DNA-binding protein inhibitor ID-2 [ipi.MOUSE.v3.06.fasta]
  • inhibitor of DNA binding 2 [Mus musculus]gi|31565598|gb|AAH53699.1| Inhibitor of DNA binding 2 [Mus musculus]gi|13905248|gb|AAH06921.1| Inhibitor of DNA binding 2 [Mus musculus]gi|8039784|sp|P41136|ID2_MOUSE DNA-binding protein inhibitor ID-2gi|342074 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 DNA-binding protein inhibitor ID-2 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_010496) inhibitor of DNA binding 2 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • inhibitor of DNA binding 2 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Inhibitor of DNA binding 2 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • helix-loop-helix protein Id2 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 DNA-BINDING PROTEIN INHIBITOR ID-2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Id2 DNA-binding protein inhibitor ID-2 [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Id2 DNA-binding protein inhibitor ID-2 ENSMUSG00000020644 IPI00111448 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • DNA-binding protein inhibitor ID-2 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00111448.1|SWISS-PROT:P41136|TREMBL:Q545T4|ENSEMBL:ENSMUSP00000020974|REFSEQ:NP_034626 Tax_Id=10090 Gene_Symbol=Id2 DNA-binding protein inhibitor ID-2 [ipi.MOUSE.fasta.20090209]
  • DNA-binding protein inhibitor ID-2 OS=Mus musculus GN=Id2 [011711_HMR.fasta]
  • sp|P41136|ID2_MOUSE DNA-binding protein inhibitor ID-2 OS=Mus musculus GN=Id2 PE=1 SV=3 [uniprot.sptr.mouse.20130102]
  • tr|Q545T4|Q545T4_MOUSE Inhibitor of DNA binding 2 OS=Mus musculus GN=Id2 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • Inhibitor of DNA binding 2 OS=Mus musculus GN=Id2 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
  • Isoform of P41136, DNA-binding protein inhibitor ID-2 OS=Mus musculus GN=Id2 PE=1 SV=1 [MOUSE.fasta.20160308]
    • Organism: Mus musculus
    Length: 134 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IDA]
    cytoplasm [IDA]
    cytosol [UNKNOWN]
    chromatin [UNKNOWN]
    Biological Process: multicellular organismal development [IEA]
    positive regulation of cell proliferation [UNKNOWN]
    positive regulation of cell cycle [UNKNOWN]
    enucleate erythrocyte differentiation [IGI]
    embryonic gut morphogenesis [IDA]
    lymph node development [TAS]
    regulation of transcription [IEA]
    bundle of His development [IMP]
    negative regulation of transcription from RNA polymerase II promoter [UNKNOWN][IGI]
    heart development [IGI]
    cellular response to lithium ion [IDA]
    mammary gland alveolus development [IMP]
    positive regulation of macrophage differentiation [IGI]
    mammary gland epithelial cell proliferation [IMP]
    response to protein stimulus [IDA]
    Molecular Function: protein binding [IPI]
    transcription regulator activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVT  60
   61 KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF 120
  121 PSELMSNDSK VLCG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..134] PSI-BLAST 10.30103 Solution Structure of Max B-HLH-LZ

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  5.38658950816179 bayes_pls_golite062009
  • DNA binding
    		•  5.18654839258297 bayes_pls_golite062009
  • nucleic acid binding
    		•  5.05768805749761 bayes_pls_golite062009
  • transcription factor activity
    		•  4.78039531631248 bayes_pls_golite062009
  • binding
    		•  3.81829206350975 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.39500382187264 bayes_pls_golite062009
  • protein binding
    		•  2.64975291677725 bayes_pls_golite062009
  • transcription factor binding
    		•  2.61163564741984 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.58751248599889 bayes_pls_golite062009
  • transcription activator activity
    		•  2.5495467409976 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  2.42306484786159 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.31910036997977 bayes_pls_golite062009
  • transcription corepressor activity
    		•  2.03674713048499 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.52770895937238 bayes_pls_golite062009
  • promoter binding
    		•  0.8576109846276 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.53175615551166 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.3513586903977 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.20674648626116 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle