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Protein Overview: TFPI2_MOUSE

General Information:
Name(s) found: TFPI2_MOUSE [Swiss-Prot]
Description(s) found:
Found 33 descriptions.
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  • Tissue factor pathway inhibitor 2 OS=Mus musculus GN=Tfpi2 PE=2 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 230 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEA]
    Biological Process: blood coagulation [IEA]
    Molecular Function: peptidase inhibitor activity [IEA]
    serine-type endopeptidase inhibitor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPAMPLQLW NLPLLLVGSV LGLTSVSAQG NNLEICLLPL DAGPCQALIP KFYYDRDQQK  60
   61 CRRFNYGGCL GNANNFHSRD LCQQTCGSIE KVPPVCRSEL KTYPCDKPNI RFFFNLNTMT 120
  121 CEPLRPGLCS RTINVFSEEA TCKGLCEPRK HIPSFCSSPK DEGLCSANVT RFYFNSRNKT 180
  181 CETFTYTGCG GNENNFYYLD ACHRACVKGW KKPKRWKIGD FLPRFWKHLS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..162] PSI-BLAST 23.0 X-RAY STRUCTURE OF BIKUNIN FROM THE HUMAN INTER-ALPHA-INHIBITOR COMPLEX
    2 View Details [163..230] PSI-BLAST 13.69897 Alzheimer's amyloid B-protein precursor, APPI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase inhibitor activity
    		•  0.25293549040514 bayes_pls_golite062009
  • extracellular matrix structural constituent
    		•  0.20228830453365 bayes_pls_golite062009
  • enzyme inhibitor activity
    		•  0.0325480717581303 bayes_pls_golite062009
    2
    Term Confidence Notes
  • peptidase inhibitor activity
    		•  0.25293549040514 bayes_pls_golite062009
  • extracellular matrix structural constituent
    		•  0.20228830453365 bayes_pls_golite062009
  • enzyme inhibitor activity
    		•  0.0325480717581303 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle