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Protein Overview: TCF21_MOUSE

General Information:
Name(s) found: TCF21_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|74183148|dbj|BAE22527.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74178768|dbj|BAE34032.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|6755732|ref|NP_035675.1| transcription factor 21 [Mus musculus] [NCBI NR]
  • gi|31566110|gb|AAH53525.1| Transcription factor 21 [Mus musculus] [NCBI NR]
  • gi|2921851|gb|AAC62531.1| epicardin [Mus musculus] [NCBI NR]
  • gi|2745885|gb|AAC62513.1| mesoderm-specific basic-helix-loop-helix protein; Pod-1 [Mus musculus] [NCBI NR]
  • gi|2696118|dbj|BAA23883.1| nephgonadin [Mus musculus] [NCBI NR]
  • gi|2695695|gb|AAC23537.1| capsulin [Mus musculus] [NCBI NR]
  • gi|2613019|gb|AAB84256.1| basic helix-loop-helix factor Cor1 [Mus musculus] [NCBI NR]
  • gi|15214318|sp|O35437.1|TCF21_MOUSE RecName: Full=Transcription factor 21; AltName: Full=Podocyte-expressed 1; Short=Pod-1; AltName: Full=Epicardin; AltName: Full=Capsulin [NCBI NR]
  • gi|12847789|dbj|BAB27709.1| unnamed protein product [Mus musculus] [NCBI NR]
  • (O35437) Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin) [Swiss-Prot]
  • Transcription factor 21 OS=Mus musculus GN=Tcf21 PE=2 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):10-22523386 Transcription factor 21 [hmr_yeast5_DM3-1_pombe.fasta]
  • transcription factor 21; podocyte-expressed 1 [HMR_022704-rand.fasta]
  • Transcription factor 21 [ipi.MOUSE.v3.06.fasta]
  • transcription factor 21 [Mus musculus]gi|31566110|gb|AAH53525.1| Transcription factor 21 [Mus musculus]gi|2613019|gb|AAB84256.1| basic helix-loop-helix factor Cor1 [Mus musculus]gi|15214318|sp|O35437|TF21_MOUSE Transcription factor 21 (Podocyte-express [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Transcription factor 21 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_011545) transcription factor 21; podocyte-expressed 1 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • transcription factor 21 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Transcription factor 21 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • basic helix-loop-helix factor Cor1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • epicardin [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • mesoderm-specific basic-helix-loop-helix protein; Pod-1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • capsulin [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • nephgonadin [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 TRANSCRIPTION FACTOR 21 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Tcf21 Transcription factor 21 [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Tcf21 Transcription factor 21 ENSMUSG00000045680 IPI00130736 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • IPI:IPI00130736.1|SWISS-PROT:O35437|ENSEMBL:ENSMUSP00000053178|REFSEQ:NP_035675 Tax_Id=10090 Gene_Symbol=Tcf21 Transcription factor 21 [ipi.MOUSE.fasta.20090209]
  • Transcription factor 21 OS=Mus musculus GN=Tcf21 [011711_HMR.fasta]
  • sp|O35437|TCF21_MOUSE Transcription factor 21 OS=Mus musculus GN=Tcf21 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
    • Organism: Mus musculus
    Length: 179 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IC]
    Biological Process: respiratory system development [IMP]
    reproductive structure development [IMP]
    transcription [IEA]
    lung vasculature development [IMP]
    spleen development [IMP]
    embryonic digestive tract morphogenesis [UNKNOWN]
    gland development [UNKNOWN]
    sex determination [IMP]
    regulation of transcription [IEA]
    bronchiole development [IMP]
    lung morphogenesis [IMP]
    organ morphogenesis [IMP]
    epithelial cell differentiation [IMP]
    morphogenesis of a branching structure [IMP]
    lung alveolus development [IMP]
    sex differentiation [IMP]
    glomerulus development [IMP]
    negative regulation of transcription, DNA-dependent [IDA]
    kidney development [IMP]
    ureteric bud development [IMP]
    positive regulation of transcription, DNA-dependent [IDA]
    branching involved in ureteric bud morphogenesis [IMP]
    vasculature development [IMP]
    Molecular Function: DNA binding [IEA]
    transcription factor activity [IDA]
    protein binding [IPI]
    transcription regulator activity [IEA]
    protein dimerization activity [IPI]
    sequence-specific DNA binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTGSLSDVE DLQEVEMLDC DSLKVDSNKE FGTSNESTEE GSNCENGSPQ KGRGGLGKRR  60
   61 KAPTKKSPLS GVSQEGKQVQ RNAANARERA RMRVLSKAFS RLKTTLPWVP PDTKLSKLDT 120
  121 LRLASSYIAH LRQILANDKY ENGYIHPVNL TWPFMVAGKP ENDLKEVVTA NRLCGTTAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..179] PSI-BLAST 16.221849 Myc prot-oncogene protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.04189889011459 bayes_pls_golite062009
  • DNA binding
    		•  1.57198412842008 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.51367486803231 bayes_pls_golite062009
  • transcription factor activity
    		•  1.48896865387791 bayes_pls_golite062009
  • protein binding
    		•  0.90375176425983 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.863712081656127 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle