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Protein Overview: CE39207

General Information:
Name(s) found: CE39207 [WormBase]
Description(s) found:
Found 10 descriptions.
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  • WBGene00015266 status:Partially_confirmed UniProt:Q965N3 protein_id:CCD62274.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 738 amino acids

    Gene Ontology:
    Cellular Component: exosome (RNase complex) [IEALink to PubMed article]
    Biological Process: RNA processing [IEALink to PubMed article]
    mRNA catabolic process [IEALink to PubMed article]
    Molecular Function: 3'-5'-exoribonuclease activity [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]
    exoribonuclease activity, producing 5'-phosphomonoesters [IEALink to PubMed article]
    polyribonucleotide nucleotidyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLSRLPIHI SKRFHTKEYR LAGREQSVAV DFDGKSGIEL KAGHLARFAS STVVASFGDN  60
   61 AVMATVVQRK SKQGDGSGVP LQVEYRPSAS AIGRIPTNFL RRELSQSDNE ILISRAIDRS 120
  121 IRPLLPGNSY ETQIICKPLA LDENADQIML GINAASTALQ ISSAAYNGPL AALRVARTAR 180
  181 GDFHVNPTQE ELREASLNLI VAMRKHEKTV MIELDGRESS AEHLEHALDV AFRHVAKLHE 240
  241 AMEQLTAEPK DELASEDFSG LERLLEETAR ERIYYVITDA GHDKISRDME IKAIFEEICA 300
  301 EKAFQTCEKD AIYRTYSTLV KKVLRDTTLR TGIRCDGRRP DEFRPITIHV DMYKKLHGCS 360
  361 IFQRGQTQVM STVTFDSPAA AFHPDSVAQL LGSQRKKSFM LHYEFPGFAI NEFGTTRSLN 420
  421 RREIGHGALA EKSLKNLFPA DFPYATRLAC QVLESNGSSS MASVCGGSLA LFDAGVPMKN 480
  481 AAAGVAIGLI SDEAEPETKY RVLTDILGIE DYAGDMDFKV AGTRDGFTAA QLDVKNGGLT 540
  541 RRQLTESLQA ARAGIDHVLQ KMSVMRDRPR EQFKPTVPII QSMRIEPHKR VTLFRNNGYN 600
  601 CKLIEAETGV KISAEDEAHI SLLAQDKEKL QKAMDMMNDV LESNSTLDFA FGSIVQAEIV 660
  661 EIIERGVYLT LPGSSRRIFM SNNHLSLNPV RHPDVLGLKI GDKMSVHWFG RDEHTGNIRL 720
  721 SRKTLAGAKT PATSQKKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..738] PSI-BLAST 152.0 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribonuclease activity
    		•  3.62650207668685 bayes_pls_golite062009
  • exoribonuclease activity
    		•  2.49584565422948 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  2.48625785660839 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  2.46667410843173 bayes_pls_golite062009
  • RNA binding
    		•  1.54417931838494 bayes_pls_golite062009
  • hydrolase activity
    		•  1.18773479836745 bayes_pls_golite062009
  • transcription termination factor activity
    		•  1.01993495617192 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • binding
    		•  0.872512498570204 bayes_pls_golite062009
  • ATP-dependent peptidase activity
    		•  0.66778558090199 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.666538467028341 bayes_pls_golite062009
  • mRNA binding
    		•  0.6661659753234 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.609202649585287 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.59064223556107 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  0.51810239718467 bayes_pls_golite062009
    		• 0.416217645025381 bayes_pls_golite062009
  • structural molecule activity
    		•  0.36020344477758 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.348601923227652 bayes_pls_golite062009
  • nuclease activity
    		•  0.262228287184671 bayes_pls_golite062009
  • DNA binding
    		•  0.237793607944966 bayes_pls_golite062009
  • protein binding
    		•  0.0913090112555771 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0287026367466632 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle