Protein Overview: ALX1_MOUSE

General Information:
Name(s) found:	ALX1_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|67460551\|sp\|Q8C8B0.1\|ALX1_MOUSE RecName: Full=ALX homeobox protein 1; AltName: Full=Cartilage homeoprotein 1; Short=CART-1 [NCBI NR] gi\|30353921\|gb\|AAH52200.1\| ALX homeobox 1 [Mus musculus] [NCBI NR] gi\|27369774\|ref\|NP_766141.1\| ALX homeobox 1 [Mus musculus] [NCBI NR] gi\|26339004\|dbj\|BAC33173.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|148689727\|gb\|EDL21674.1\| cartilage homeo protein 1 [Mus musculus] [NCBI NR] Cartilage homeoprotein 1 - Mus musculus (Mouse) [Swiss-Prot] ALX homeobox protein 1 OS=Mus musculus GN=Alx1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):10-102456278 Cartilage homeo protein 1 [hmr_yeast5_DM3-1_pombe.fasta] cartilage homeo protein 1 [HMR_022704-rand.fasta] Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130005I02 product:cartilage homeo protein 1, full insert sequence [ipi.MOUSE.v3.06.fasta] cartilage homeo protein 1 [Mus musculus]gi\|30353921\|gb\|AAH52200.1\| Cartilage homeo protein 1 [Mus musculus]gi\|26339004\|dbj\|BAC33173.1\| unnamed protein product [Mus musculus] [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Cartilage homeoprotein 1 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] cartilage homeo protein 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Tax_Id=10090 Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130005I02 product:cartilage homeo protein 1, full insert sequence [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] ALX homeobox protein 1 (Cartilage homeoprotein 1) (CART-1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] ALX homeobox 1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 MUS MUSCULUS 16 DAYS EMBRYO HEAD CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:C130005I02 PRODUCT:CARTILAGE HOMEO PROTEIN 1, FULL INSERT SEQUENCE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Alx1 ALX homeobox protein 1 [mouse-ipi-250309-contam.fasta] Cartilage homeo protein 1 [Mus musculus] [nr-271106-contam.fasta] Cartilage homeoprotein 1 (CART-1) [nr-271106-contam.fasta] Tax_Id=10090 Gene_Symbol=Cart1 Cartilage homeoprotein 1 [zeeyong.fasta] Tax_Id=10090 Gene_Symbol=Alx1 ALX homeobox protein 1 ENSMUSG00000036602 IPI00227026 [IPIxENS.MOUSE_plus_REVERSE.fasta] ALX homeobox protein 1 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00227026.1\|SWISS-PROT:Q8C8B0\|ENSEMBL:ENSMUSP00000042512\|REFSEQ:NP_766141 Tax_Id=10090 Gene_Symbol=Alx1 ALX homeobox protein 1 [ipi.MOUSE.fasta.20090209] ALX homeobox protein 1 OS=Mus musculus GN=Alx1 [011711_HMR.fasta] sp\|Q8C8B0\|ALX1_MOUSE ALX homeobox protein 1 OS=Mus musculus GN=Alx1 PE=1 SV=1 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	326 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN] transcription factor complex [IDA]
Biological Process:	negative regulation of transcription from RNA polymerase II promoter [UNKNOWN] embryonic limb morphogenesis [IGI] neural tube closure [IMP] multicellular organismal development [IEA] mesenchymal cell development [IMP] palate development [IGI] anterior/posterior pattern formation [IGI] regulation of transcription, DNA-dependent [IEA] regulation of transcription [IEA] positive regulation of transcription from RNA polymerase II promoter [IDA][IGI] embryonic skeletal system morphogenesis [IGI]
Molecular Function:	DNA binding [IEA] transcription factor activity [UNKNOWN][IDA] transcription regulator activity [IEA] protein heterodimerization activity [IPI] sequence-specific DNA binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEFLSEKFAL KSPPSKNSDF YMGTGGALEH VMETLDNESF YGKATAGKCV QAFGPLPRAE  60
   61 HHVRLDRTSP CQDSSVNYGI TKVEGQPLHT ELNRAMDNCN NLRMSPVKGM PEKSELDELG 120
  121 DKCDSNVSSS KKRRHRTTFT SLQLEELEKV FQKTHYPDVY VREQLALRTE LTEARVQVWF 180
  181 QNRRAKWRKR ERYGQIQQAK SHFAATYDIS VLPRTDSYPQ IQNNLWAGNA SGGSVVTSCM 240
  241 LPRDASSCMT PYSHSPRTDS SYTGFSNHQN QFSHVPLNNF FTDSLLTGAT NGHAFETKPE 300
  301 FERRSSSIAV LRMKAKEHTA NISWAM

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: ALX1_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: