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Protein Overview: PNK1_SCHPO

General Information:
Name(s) found: PNK1_SCHPO [Swiss-Prot]
Description(s) found:
Found 2 descriptions.
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  • Bifunctional polynucleotide phosphatase/kinase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pnk1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Schizosaccharomyces pombe 972h-
    Length: 421 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKKRKSPP QESLTSYFEK SSKSSKKYGS QNKDSDSSST CLQQKIEIQW SITDSLYIAK  60
   61 YGKLKKTKKF IAFDLDGTLI KTKSGRVFSK DAADWTWWHP SVVPKLKALY QDNYSLVIFS 120
  121 NQNGIPRKPS AGHTFQMKIR AIFESLDLPI VLYAAILKDK FRKPLTGMWN SFLKDVNRSI 180
  181 DLSFIKYVGD AAGRPGDHNS TDLKFAENIG IKFETPEQFF LGHSFVPPNF ESFHPKNYLV 240
  241 RNSSSHPYHF KKSEHQEIVV LVGFPSSGKS TLAESQIVTQ GYERVNQDIL KTKSKCIKAA 300
  301 IEALKKEKSV VIGMYSIIST TYAISDNTNP TIESRKMWID IAQEFEIPIR CIHLQSSEEL 360
  361 ARHNNVFRYI HHNQKQLPEI AFNSFKSRFQ MPTVEEGFTN VEEVPFKCLK DYEDTWNYWY 420
  421 E

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..421] PSI-BLAST 66.09691 Molecular architecture of mammalian polynucleotide kinase, a DNA repair enzyme

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  2.8454129466116 bayes_pls_golite062009
  • catalytic activity
    		•  1.55296860681783 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.35602953485803 bayes_pls_golite062009
  • ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
    		•  1.11898265155482 bayes_pls_golite062009
  • polynucleotide kinase activity
    		•  1.11898265155482 bayes_pls_golite062009
  • polydeoxyribonucleotide kinase activity
    		•  1.11898265155482 bayes_pls_golite062009
  • ATP-dependent polynucleotide kinase activity
    		•  1.11898265155482 bayes_pls_golite062009
  • binding
    		•  0.89911057995199 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.622587075720369 bayes_pls_golite062009
  • DNA binding
    		•  0.452491037562571 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.35576808478553 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.317638328626539 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.289666831374877 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.267902691361304 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.267204331913108 bayes_pls_golite062009
  • ATPase activity
    		•  0.19237422649759 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle