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Protein Overview: ULK1_MOUSE

General Information:
Name(s) found: ULK1_MOUSE [Swiss-Prot]
Description(s) found:
Found 17 descriptions.
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  • Serine/threonine-protein kinase ULK1 OS=Mus musculus GN=Ulk1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 1051 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDA]
    cytoplasmic vesicle membrane [IDA]
    cytoplasm [IDA]
    neuronal cell body [IDA]
    neuron projection [IDA]
    Biological Process: cerebellar granule cell differentiation [IMP]
    radial glia guided migration of granule cell [IMP]
    signal transduction [IEA]
    neuron projection development [UNKNOWN][IMP]
    protein amino acid autophosphorylation [IDA]
    auxin biosynthetic process [IEA]
    Ras protein signal transduction [IDA]
    protein amino acid phosphorylation [IEA]
    negative regulation of collateral sprouting [IMP]
    axon extension [IMP]
    regulation of nerve growth factor receptor signaling pathway [IMP]
    autophagy [IEA]
    axonogenesis [IDA]
    neuron projection regeneration [UNKNOWN]
    receptor internalization [IMP]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    protein binding [IPI]
    protein kinase activity [IDA]
    protein serine/threonine kinase activity [IEA]
    transferase activity [IEA]
    kinase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPGRGGVET VGKFEFSRKD LIGHGAFAVV FKGRHREKHD LEVAVKCINK KNLAKSQTLL  60
   61 GKEIKILKEL KHENIVALYD FQEMANSVYL VMEYCNGGDL ADYLHTMRTL SEDTVRLFLQ 120
  121 QIAGAMRLLH SKGIIHRDLK PQNILLSNPG GRRANPSNIR VKIADFGFAR YLQSNMMAAT 180
  181 LCGSPMYMAP EVIMSQHYDG KADLWSIGTI VYQCLTGKAP FQASSPQDLR LFYEKNKTLV 240
  241 PAIPRETSAP LRQLLLALLQ RNHKDRMDFD EFFHHPFLDA STPIKKSPPV PVPSYPSSGS 300
  301 GSSSSSSSAS HLASPPSLGE MPQLQKTLTS PADAAGFLQG SRDSGGSSKD SCDTDDFVMV 360
  361 PAQFPGDLVA EAASAKPPPD SLLCSGSSLV ASAGLESHGR TPSPSPTCSS SPSPSGRPGP 420
  421 FSSNRYGASV PIPVPTQVHN YQRIEQNLQS PTQQQTARSS AIRRSGSTTP LGFGRASPSP 480
  481 PSHTDGAMLA RKLSLGGGRP YTPSPQVGTI PERPSWSRVP SPQGADVRVG RSPRPGSSVP 540
  541 EHSPRTTGLG CRLHSAPNLS DFHVVRPKLP KPPTDPLGAT FSPPQTSAPQ PCPGLQSCRP 600
  601 LRGSPKLPDF LQRSPLPPIL GSPTKAGPSF DFPKTPSSQN LLTLLARQGV VMTPPRNRTL 660
  661 PDLSEASPFH GQQLGSGLRP AEDTRGPFGR SFSTSRITDL LLKAAFGTQA SDSGSTDSLQ 720
  721 EKPMEIAPSA GFGGTLHPGA RGGGASSPAP VVFTVGSPPS GATPPQSTRT RMFSVGSSSS 780
  781 LGSTGSSSAR HLVPGACGEA PELSAPGHCC SLADPLAANL EGAVTFEAPD LPEETLMEQE 840
  841 HTETLHSLRF TLAFAQQVLE IAALKGSASE AAGGPEYQLQ ESVVADQISQ LSREWGFAEQ 900
  901 LVLYLKVAEL LSSGLQTAID QIRAGKLCLS STVKQVVRRL NELYKASVVS CQGLSLRLQR 960
  961 FFLDKQRLLD GIHGVTAERL ILSHAVQMVQ SAALDEMFQH REGCVPRYHK ALLLLEGLQH1020
 1021 TLTDQADIEN IAKCKLCIER RLSALLSGVY A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle