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Protein Overview: 4EBP2_MOUSE

General Information:
Name(s) found: 4EBP2_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|74203825|dbj|BAE28514.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|6753742|ref|NP_034254.1| eukaryotic translation initiation factor 4E binding protein 2 [Mus musculus] [NCBI NR]
  • gi|34921444|sp|P70445.1|4EBP2_MOUSE RecName: Full=Eukaryotic translation initiation factor 4E-binding protein 2; Short=eIF4E-binding protein 2; Short=4E-BP2; AltName: Full=Phosphorylated heat- and acid-stable protein regulated by insulin 2; Short=PHAS-II [NCBI NR]
  • gi|1658516|gb|AAC52899.1| PHAS-II [Mus musculus] [NCBI NR]
  • gi|15929279|gb|AAH15082.1| Eif4ebp2 protein [Mus musculus] [NCBI NR]
  • gi|148700196|gb|EDL32143.1| mCG15757, isoform CRA_a [Mus musculus] [NCBI NR]
  • gi|148700195|gb|EDL32142.1| mCG15757, isoform CRA_a [Mus musculus] [NCBI NR]
  • gi|110611863|gb|AAI19540.1| Eif4ebp2 protein [Mus musculus] [NCBI NR]
  • Eukaryotic translation initiation factor 4E-binding protein 2 OS=Mus musculus GN=Eif4ebp2 PE=1 SV=1 [Swiss-Prot]
  • (P70445) Eukaryotic translation initiation factor 4E binding protein 2 (4E-BP2) (eIF4E-binding protein 2) (Phosphorylated heat- and acid-stable protein regulated by insulin 2) (PHAS-II) [Swiss-Prot]
  • Ensembl_locations(Chr-bp):10-61080861 PHAS-II [hmr_yeast5_DM3-1_pombe.fasta]
  • eukaryotic translation initiation factor 4E binding protein 2 [HMR_022704-rand.fasta]
  • Eukaryotic translation initiation factor 4E binding protein 2 [ipi.MOUSE.v3.06.fasta]
  • Eif4ebp2 protein [Mus musculus]gi|6753742|ref|NP_034254.1| eukaryotic translation initiation factor 4E binding protein 2 [Mus musculus]gi|34921444|sp|P70445|4BP2_MOUSE Eukaryotic translation initiation factor 4E binding protein 2 (4E-BP2) (eIF4E-binding [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Eukaryotic translation initiation factor 4E-binding protein 2 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_010124) eukaryotic translation initiation factor 4E binding protein 2 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • eukaryotic translation initiation factor 4E binding protein 2 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Tax_Id=10090 Eukaryotic translation initiation factor 4E binding protein 2 [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta]
  • Eukaryotic translation initiation factor 4E-binding protein 2 (eIF4E-binding protein 2) (4E-BP2) (Phosphorylated heat- and acid-stable protein regulated by insulin 2) (PHAS-II) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • mCG15757, isoform CRA_a [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Eif4ebp2 protein [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • PHAS-II [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E BINDING PROTEIN 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Eif4ebp2 Eukaryotic translation initiation factor 4E-binding protein 2 [mouse-ipi-250309-contam.fasta]
  • Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) (eIF4E-binding protein 2) (Phosphorylated heat- and acid-stable protein regulated by insulin 2) (PHAS-II) [nr-271106-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Eif4ebp2 Eukaryotic translation initiation factor 4E-binding protein 2 ENSMUSG00000020091 IPI00109318 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • eukaryotic translation initiation factor 4E-binding protein 2 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00109318.1|SWISS-PROT:P70445|TREMBL:Q3UFP6;Q3UZD4|ENSEMBL:ENSMUSP00000020288|REFSEQ:NP_034254 Tax_Id=10090 Gene_Symbol=Eif4ebp2 Eukaryotic translation initiation factor 4E-binding protein 2 [ipi.MOUSE.fasta.20090209]
  • Eukaryotic translation initiation factor 4E-binding protein 2 OS=Mus musculus GN=Eif4ebp2 [011711_HMR.fasta]
  • Eukaryotic translation initiation factor 4E-binding protein 2 OS=Mus musculus GN=Eif4ebp2 PE=2 SV=1 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta]
  • sp|P70445|4EBP2_MOUSE Eukaryotic translation initiation factor 4E-binding protein 2 OS=Mus musculus GN=Eif4ebp2 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • tr|Q3UFP6|Q3UFP6_MOUSE Eif4ebp2 protein OS=Mus musculus GN=Eif4ebp2 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • Eif4ebp2 protein OS=Mus musculus GN=Eif4ebp2 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
  • Isoform of P70445, Eif4ebp2 protein OS=Mus musculus GN=Eif4ebp2 PE=1 SV=1 [MOUSE.fasta.20160308]
    • Organism: Mus musculus
    Length: 120 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: regulation of translation [IEA]
    negative regulation of translational initiation [IEA]
    insulin receptor signaling pathway [IDA]
    regulation of translational initiation [TAS]
    negative regulation of translation [IEA]
    cAMP-mediated signaling [IDA]
    Molecular Function: protein binding [IPI]
    eukaryotic initiation factor 4E binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASAGGSHQ PSQSRAIPTR TVAISDAAQL PQDYCTTPGG TLFSTTPGGT RIIYDRKFLL  60
   61 DRRNSPMAQT PPCHLPNIPG VTSPGALIED SKVEVNNLNN LNNHDRKHAV GDEAQFEMDI 120
  121

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..120] Pfam 90.187087 No description for PF05456.2 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle