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Protein Overview: CRYAA_MOUSE

General Information:
Name(s) found: CRYAA_MOUSE [Swiss-Prot]
Description(s) found:
Found 28 descriptions.
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  • Alpha-crystallin A chain OS=Mus musculus GN=Cryaa PE=2 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 196 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [UNKNOWN][IDA]
    Biological Process: apoptosis involved in morphogenesis [IGI]
    lens fiber cell morphogenesis [IMP]
    tubulin complex assembly [IMP]
    protein homooligomerization [UNKNOWN]
    actin filament organization [IMP]
    response to hydrogen peroxide [UNKNOWN][IMP]
    protein folding [UNKNOWN]
    lens development in camera-type eye [IGI][IMP]
    lens morphogenesis in camera-type eye [IMP]
    mitochondrion organization [IMP]
    negative regulation of gene expression [IMP]
    response to UV-A [IMP]
    response to heat [IEA]
    positive regulation of cell growth [IMP]
    response to hypoxia [IMP]
    negative regulation of apoptosis [IMP]
    negative regulation of caspase activity [IGI]
    M phase specific microtubule process [IMP]
    apoptosis [IMP]
    camera-type eye development [IGI]
    embryonic camera-type eye morphogenesis [IMP]
    positive regulation of protein amino acid phosphorylation [IMP]
    Molecular Function: identical protein binding [UNKNOWN]
    protein binding [IPI]
    structural constituent of eye lens [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVTIQHPWF KRALGPFYPS RLFDQFFGEG LFEYDLLPFL SSTISPYYRQ SLFRTVLDSG  60
   61 ISELMTHMWF VMHQPHAGNP KNNPVKVRSD RDKFVIFLDV KHFSPEDLTV KVLEDFVEIH 120
  121 GKHNERQDDH GYISREFHRR YRLPSNVDQS ALSCSLSADG MLTFSGPKVQ SGLDAGHSER 180
  181 AIPVSREEKP SSAPSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..196] PSI-BLAST 10.221849 CRYSTAL STRUCTURE AND ASSEMBLY OF TSP36, A METAZOAN SMALL HEAT SHOCK PROTEIN


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle