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Protein Overview: POMT2

General Information:
Name(s) found: POMT2 [HGNC (HUGO)]
Description(s) found:
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  • gi|7417476|gb|AAF62558.1|AC007954_3 POMT2 [Homo sapiens] [NCBI NR]
  • gi|32455271|ref|NP_037514.2| protein-O-mannosyltransferase 2 [Homo sapiens] [NCBI NR]
  • gi|32171723|sp|Q9UKY4.2|POMT2_HUMAN RecName: Full=Protein O-mannosyl-transferase 2; AltName: Full=Dolichyl-phosphate-mannose--protein mannosyltransferase 2 [NCBI NR]
  • gi|21619461|gb|AAH31651.1| Protein-O-mannosyltransferase 2 [Homo sapiens] [NCBI NR]
  • protein-O-mannosyltransferase 2 [HGNC (HUGO)]
  • (Q9UKY4) Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 2) [Swiss-Prot]
  • Protein O-mannosyl-transferase 2 OS=Homo sapiens GN=POMT2 PE=1 SV=2 [Swiss-Prot]
  • Splice isoform 1 of Q9UKY4 [hmr_yeast5_DM3-1_pombe.fasta]
  • putative protein O-mannosyltransferase [HMR_022704.fasta]
  • putative protein O-mannosyltransferase [Homo sapiens]gi|21619461|gb|AAH31651.1| Putative protein O-mannosyltransferase [Homo sapiens]gi|7417476|gb|AAF62558.1| POMT2 [Homo sapiens]gi|32171723|sp|Q9UKY4|POT2_HUMAN Protein O-mannosyl-transferase 2 (Dolich [nrdb_11152004_Chlamydomonas]
  • Protein O-mannosyl-transferase 2 (Dolichyl-phosphate-mannose--protein mannosyltransferase 2) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Protein O-mannosyl-transferase 2 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • putative protein O-mannosyltransferase [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • protein O-mannosyltransferase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Protein-O-mannosyltransferase 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • POMT2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of Protein O-mannosyl-transferase 2 [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 1 OF PROTEIN O-MANNOSYL-TRANSFERASE 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Protein O-mannosyl-transferase 2; AltName: Full=Dolichyl-phosphate-mannose--protein mannosyltransferase 2 [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=POMT2 Isoform 1 of Protein O-mannosyl-transferase 2 [human-ipi-250309-contam.fasta]
  • protein-O-mannosyltransferase 2 [Homo sapiens] [NCBI-RefSeq_human_na_07-13-2009_con_reversed.fasta]
  • IPI:IPI00329648.3|SWISS-PROT:Q9UKY4-1|TREMBL:Q6AHY3|ENSEMBL:ENSP00000261534|REFSEQ:NP_037514|H-INV:HIT000084333|VEGA:OTTHUMP00000028471 Tax_Id=9606 Gene_Symbol=POMT2 Isoform 1 of Protein O-mannosyl-transferase 2 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=POMT2 Isoform 1 of Protein O-mannosyl-transferase 2 ENSG00000009830 IPI00329648 IPI00556213 IPI00329649 [drosphohumanreversed.fasta]
  • protein O-mannosyl-transferase 2 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q9UKY4;Q9NSG6;Q9P1W0;Q9P1W2; RecName: Full=Protein O-mannosyl-transferase 2; AltName: Full=Dolichyl-phosphate-mannose--protein mannosyltransferase 2; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Protein O-mannosyl-transferase 2 OS=Homo sapiens GN=POMT2 [011711_HMR.fasta]
  • GeneSymbol=POMT2 Synonyms=DKFZp686G10254|FLJ22309|MDDGA2|MDDGB2|MDDGC2 protein O-mannosyl-transferase 2 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00329648.3|SWISS-PROT:Q9UKY4-1|TREMBL:Q6AHY3|ENSEMBL:ENSP00000261534|REFSEQ:NP_037514|H-INV:HIT000084333 Tax_Id=9606 Gene_Symbol=POMT2 Isoform 1 of Protein O-mannosyl-transferase 2 [ipi.HUMAN.20110912.fasta]
  • Protein O-mannosyl-transferase 2 GN=POMT2 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 750 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPATGGGLA ESELRPRRGR CGPQAARAAG RDVAAEAVAR SPKRPAWGSR RFEAVGWWAL  60
   61 LALVTLLSFA TRFHRLDEPP HICWDETHFG KMGSYYINRT FFFDVHPPLG KMLIGLAGYL 120
  121 SGYDGTFLFQ KPGDKYEHHS YMGMRGFCAF LGSWLVPFAY LTVLDLSKSL SAALLTAALL 180
  181 TFDTGCLTLS QYILLDPILM FFIMAAMLSM VKYNSCADRP FSAPWWFWLS LTGVSLAGAL 240
  241 GVKFVGLFII LQVGLNTIAD LWYLFGDLSL SLVTVGKHLT ARVLCLIVLP LALYTATFAV 300
  301 HFMVLSKSGP GDGFFSSAFQ ARLSGNNLHN ASIPEHLAYG SVITVKNLRM AIGYLHSHRH 360
  361 LYPEGIGARQ QQVTTYLHKD YNNLWIIKKH NTNSDPLDPS FPVEFVRHGD IIRLEHKETS 420
  421 RNLHSHYHEA PMTRKHYQVT GYGINGTGDS NDFWRIEVVN RKFGNRIKVL RSRIRFIHLV 480
  481 TGCVLGSSGK VLPKWGWEQL EVTCTPYLKE TLNSIWNVED HINPKLPNIS LDVLQPSFPE 540
  541 ILLESHMVMI RGNSGLKPKD NEFTSKPWHW PINYQGLRFS GVNDTDFRVY LLGNPVVWWL 600
  601 NLLSIALYLL SGSIIAVAMQ RGARLPAEVA GLSQVLLRGG GQVLLGWTLH YFPFFLMGRV 660
  661 LYFHHYFPAM LFSSMLTGIL WDTLLRLCAW GLASWPLARG IHVAGILSLL LGTAYSFYLF 720
  721 HPLAYGMVGP LAQDPQSPMA GLRWLDSWDF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..104] MSA 1.939991 View MSA. No confident structure predictions are available.
    2 View Details [105..333] MSA 5.994997 View MSA. No confident structure predictions are available.
    3 View Details [334..523] PSI-BLAST 53.0 Structural genomics of Caenorhabditis elegans: Structure of a protein with unknown function
    4 View Details [524..628] MSA 1.084991 View MSA. No confident structure predictions are available.
    5 View Details [629..750] MSA 1.083996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • dolichyl-phosphate-mannose-protein mannosyltransferase activity
    		•  7.33543412640964 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  6.32966341675541 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  2.60661923349025 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  2.57555885876017 bayes_pls_golite062009
  • receptor activity
    		•  1.99332745476324 bayes_pls_golite062009
  • binding
    		•  1.86366637427031 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.71523634580131 bayes_pls_golite062009
  • signal transducer activity
    		•  1.71523634580131 bayes_pls_golite062009
  • cation channel activity
    		•  1.66500687404195 bayes_pls_golite062009
  • ion channel activity
    		•  1.61859406934521 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  1.57127083095499 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  1.55374970486978 bayes_pls_golite062009
  • channel activity
    		•  1.55374970486978 bayes_pls_golite062009
  • inositol-1,4,5-trisphosphate receptor activity
    		•  1.28298370923705 bayes_pls_golite062009
  • transferase activity
    		•  0.981084601370981 bayes_pls_golite062009
  • calcium channel activity
    		•  0.85901349040585 bayes_pls_golite062009
  • catalytic activity
    		•  0.659936859803906 bayes_pls_golite062009
  • calcium-release channel activity
    		•  0.65133561512386 bayes_pls_golite062009
  • gated channel activity
    		•  0.53737429019655 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  0.52162184692236 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  0.52162184692236 bayes_pls_golite062009
  • protein binding
    		•  0.405144403982597 bayes_pls_golite062009
  • inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
    		•  0.152598505509111 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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