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Protein Overview: EIF3M

General Information:
Name(s) found: EIF3M [HGNC (HUGO)]
Description(s) found:
Found 34 descriptions.
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  • eukaryotic translation initiation factor 3, subunit M [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 374 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVPAFIDIS EEDQAAELRA YLKSKGAEIS EENSEGGLHV DLAQIIEACD VCLKEDDKDV  60
   61 ESVMNSVVSL LLILEPDKQE ALIESLCEKL VKFREGERPS LRLQLLSNLF HGMDKNTPVR 120
  121 YTVYCSLIKV AASCGAIQYI PTELDQVRKW ISDWNLTTEK KHTLLRLLYE ALVDCKKSDA 180
  181 ASKVMVELLG SYTEDNASQA RVDAHRCIVR ALKDPNAFLF DHLLTLKPVK FLEGELIHDL 240
  241 LTIFVSAKLA SYVKFYQNNK DFIDSLGLLH EQNMAKMRLL TFMGMAVENK EISFDTMQQE 300
  301 LQIGADDVEA FVIDAVRTKM VYCKIDQTQR KVVVSHSTHR TFGKQQWQQL YDTLNAWKQN 360
  361 LNKVKNSLLS LSDT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..153] MSA 4.360995 View MSA. No confident structure predictions are available.
    2 View Details [154..268] MSA 2.438993 View MSA. No confident structure predictions are available.
    3 View Details [269..374] PSI-BLAST 8.69897 Solution structure of the PCI domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  4.20828497061591 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.97631536825798 bayes_pls_golite062009
  • DNA binding
    		•  3.93431504495991 bayes_pls_golite062009
  • binding
    		•  3.38086362981788 bayes_pls_golite062009
  • transcription factor activity
    		•  3.2482889289815 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.95301685898669 bayes_pls_golite062009
  • structural molecule activity
    		•  2.70976099158766 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.8401324043677 bayes_pls_golite062009
  • transcription activator activity
    		•  1.69071209162619 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.54960543048317 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.0361110104194 bayes_pls_golite062009
  • protein binding
    		•  0.776629952382685 bayes_pls_golite062009
  • RNA binding
    		•  0.345456982950223 bayes_pls_golite062009
  • transcription factor binding
    		•  0.13558561552621 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle