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Protein Overview: gi|109473300

General Information:
Name(s) found: gi|109473300 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • gi|109473300|ref|XP_001066598.1| PREDICTED: similar to Homeodomain-interacting protein kinase 2 (Nuclear body-associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase) isoform 1 [Rattus norvegicus] [NCBI NR]
    • Organism: Rattus norvegicus
    Length: 1214 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN]
    nuclear body [UNKNOWN]
    PML body [UNKNOWN]
    cytoplasm [UNKNOWN]
    Biological Process: positive regulation of cell proliferation [UNKNOWN]
    SMAD protein signal transduction [UNKNOWN]
    transforming growth factor beta receptor signaling pathway [UNKNOWN]
    anterior/posterior pattern formation [UNKNOWN]
    smoothened signaling pathway [UNKNOWN]
    DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis [UNKNOWN]
    adult locomotory behavior [UNKNOWN]
    protein amino acid phosphorylation [IEA]
    positive regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    negative regulation of neuron apoptosis [UNKNOWN]
    DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [UNKNOWN]
    negative regulation of BMP signaling pathway [UNKNOWN]
    adult walking behavior [UNKNOWN]
    voluntary musculoskeletal movement [UNKNOWN]
    positive regulation of transcription, DNA-dependent [UNKNOWN]
    positive regulation of JNK cascade [UNKNOWN]
    positive regulation of transforming growth factor beta receptor signaling pathway [UNKNOWN]
    Molecular Function: virion binding [UNKNOWN]
    DNA binding [IEA]
    ATP binding [IEA]
    protein binding [UNKNOWN]
    SMAD binding [UNKNOWN]
    transcription corepressor activity [UNKNOWN]
    protein serine/threonine kinase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPVYEGMAS HVQVFSPHTL QSSAFCSVKK LKVEPSSNWD MTGYGSHSKV YSQSKNIPPS  60
   61 QPASTTVSTS LPIPNPSLPY EQTIIFPGST GHIVVTSASS TSVTGQVLGG PHNLMRRSTV 120
  121 SLLDTYQKCG LKRKSEEIEN TSSVQIIEEH PPMIQNNASG ATVATATTST ATSKNSGSNS 180
  181 EGDYQLVQHE VLCSMTNTYE VLEFLGRGTF GQVVKCWKRG TNEIVAIKIL KNHPSYARQG 240
  241 QIEVSILARL STESADDYNF VRAYECFQHK NHTCLVFEML EQNLYDFLKQ NKFSPLPLKY 300
  301 IRPVLQQVAT ALMKLKSLGL IHADLKPENI MLVDPSRQPY RVKVIDFGSA SHVSKAVCST 360
  361 YLQSRYYRAP EIILGLPFCE AIDMWSLGCV IAELFLGWPL YPGASEYDQI RYISQTQGLP 420
  421 AEYLLSAGTK TTRFFNRDTD SPYPLWRLKT PDDHEAETGI KSKEARKYIF NCLDDMAQVN 480
  481 MTTDLEGSDM LVEKADRREF IDLLKKMLTI DADKRITPIE TLNHPFVTMT HLLDFPHSTH 540
  541 VKSCFQNMEI CKRRVNMYDT VNQSKTPFIT HVAPSTSTNL TMTFNNQLTT VHNQTNVLRS 600
  601 APTSTSATLS LANPEVSILN YQSTLYQPSA ASMAAVAQRS MPLQTGTAQI CARPDPFQQA 660
  661 LIVCPPGFQG LQASPSKHAG YSVRMENAVP IVTQAPGAQP LQIQPGLLAQ KSITKSSNLL 720
  721 TLDPSKKHFT VDLICPPLLS CTQRESFDDQ VSREEQAWPG GAQQILLPPA WQQLTGVATH 780
  781 TSVQHAAVIP ETMAGTQQLA DWRNTHAHGS HYNPIMQQPA LLTGHVTLPA AQPLNVGVAH 840
  841 VMRQQPTSTT SSRKSKQHQS SARLEVLIIQ IFHLLGSSAT SVAASQNAFV TTRDRQRQTI 900
  901 VIPDTPSPTV SVITISSDTD EEEEQKHAPT STVSKQRKNV ISCVTVHDSP YSDSSSNTSP 960
  961 YSVQQRTGHN GTNTLDTKGG LENHCTGNPR TIIVPPLKTQ ASEVLVECTL GDEGSPLVSK1020
 1021 SSSTVTSTSG HSSGSSSGAI AYRQQRPGPH FQQQQPLNLS QAQQHMAADR TGSHRRQQAY1080
 1081 ITPTMAQAPY TFPHSSPSHG TVHPHLAAAA HLPAQPHLYT YTAPTALGST STVAHLVASQ1140
 1141 GSARHTVQHT AYPASIVHQV PVSMGPRVLP SPTIHPSQYP AQFAHQTYIS ASPASTVYTG1200
 1201 YPLSPAKVNQ YPYI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle