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A cascade of processes induced by the detection of DNA damage within a cell. A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription. A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
Acc: GO:0006978
Aspect: Biological Process
Desc: A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.
Proteins in PDR annotated with:
   This term: 25 [Search]
   Term or descendants: 25 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006978 - DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (interactive image map)
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