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Protein Overview: RARS

General Information:
Name(s) found: RARS [HGNC (HUGO)]
Description(s) found:
Found 30 descriptions.
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  • arginyl-tRNA synthetase [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 660 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVLVSECSA RLLQQEEEIK SLTAEIDRLK NCGCLGASPN LEQLQEENLK LKYRLNILRK  60
   61 SLQAERNKPT KNMINIISRL QEVFGHAIKA AYPDLENPPL LVTPSQQAKF GDYQCNSAMG 120
  121 ISQMLKTKEQ KVNPREIAEN ITKHLPDNEC IEKVEIAGPG FINVHLRKDF VSEQLTSLLV 180
  181 NGVQLPALGE NKKVIVDFSS PNIAKEMHVG HLRSTIIGES ISRLFEFAGY DVLRLNHVGD 240
  241 WGTQFGMLIA HLQDKFPDYL TVSPPIGDLQ VFYKESKKRF DTEEEFKKRA YQCVVLLQGK 300
  301 NPDITKAWKL ICDVSRQELN KIYDALDVSL IERGESFYQD RMNDIVKEFE DRGFVQVDDG 360
  361 RKIVFVPGCS IPLTIVKSDG GYTYDTSDLA AIKQRLFEEK ADMIIYVVDN GQSVHFQTIF 420
  421 AAAQMIGWYD PKVTRVFHAG FGVVLGEDKK KFKTRSGETV RLMDLLGEGL KRSMDKLKEK 480
  481 ERDKVLTAEE LNAAQTSVAY GCIKYADLSH NRLNDYIFSF DKMLDDRGNT AAYLLYAFTR 540
  541 IRSIARLANI DEEMLQKAAR ETKILLDHEK EWKLGRCILR FPEILQKILD DLFLHTLCDY 600
  601 IYELATAFTE FYDSCYCVEK DRQTGKILKV NMWRMLLCEA VAAVMAKGFD ILGIKPVQRM 660
  661

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..660] PSI-BLAST 82.39794 Arginyl-tRNA synthetase (ArgRS); Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  5.72854650987135 bayes_pls_golite062009
  • isoleucine-tRNA ligase activity
    		•  3.76808520367507 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  2.56893064485672 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.03251266786448 bayes_pls_golite062009
  • binding
    		•  0.914435503471172 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.625793556381714 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.564359271862248 bayes_pls_golite062009
  • glutamine-tRNA ligase activity
    		•  0.118292082006187 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle