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Protein Overview: LPL

General Information:
Name(s) found: LPL [HGNC (HUGO)]
Description(s) found:
Found 31 descriptions.
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  • lipoprotein lipase [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 475 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESKALLVLT LAVWLQSLTA SRGGVAAADQ RRDFIDIESK FALRTPEDTA EDTCHLIPGV  60
   61 AESVATCHFN HSSKTFMVIH GWTVTGMYES WVPKLVAALY KREPDSNVIV VDWLSRAQEH 120
  121 YPVSAGYTKL VGQDVARFIN WMEEEFNYPL DNVHLLGYSL GAHAAGIAGS LTNKKVNRIT 180
  181 GLDPAGPNFE YAEAPSRLSP DDADFVDVLH TFTRGSPGRS IGIQKPVGHV DIYPNGGTFQ 240
  241 PGCNIGEAIR VIAERGLGDV DQLVKCSHER SIHLFIDSLL NEENPSKAYR CSSKEAFEKG 300
  301 LCLSCRKNRC NNLGYEINKV RAKRSSKMYL KTRSQMPYKV FHYQVKIHFS GTESETHTNQ 360
  361 AFEISLYGTV AESENIPFTL PEVSTNKTYS FLIYTEVDIG ELLMLKLKWK SDSYFSWSDW 420
  421 WSSPGFAIQK IRVKAGETQK KVIFCSREKV SHLQKGKAPA VFVKCHDKSL NKKSG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..475] PSI-BLAST 126.0 Pancreatic lipase, C-terminal domain; Pancreatic lipase, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • galactolipase activity
    		•  6.70989838821015 bayes_pls_golite062009
  • palmitoyl-(protein) hydrolase activity
    		•  2.97710910044295 bayes_pls_golite062009
  • phospholipase A1 activity
    		•  2.92902750888377 bayes_pls_golite062009
  • triglyceride lipase activity
    		•  2.74157075059569 bayes_pls_golite062009
  • carboxylesterase activity
    		•  2.10340684157921 bayes_pls_golite062009
  • lipoprotein lipase activity
    		•  2.06238979998893 bayes_pls_golite062009
  • triglyceride binding
    		•  2.05443583869411 bayes_pls_golite062009
  • phospholipase activity
    		•  1.98964694567462 bayes_pls_golite062009
  • lipase activity
    		•  1.95656432876646 bayes_pls_golite062009
  • hydrolase activity
    		•  1.89798820741335 bayes_pls_golite062009
  • catalytic activity
    		•  1.39629727416851 bayes_pls_golite062009
  • lipoprotein binding
    		•  1.26154264842601 bayes_pls_golite062009
  • sterol esterase activity
    		•  1.21262745914703 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.985235528680562 bayes_pls_golite062009
  • peptidase activity
    		•  0.946698616106528 bayes_pls_golite062009
  • protein binding
    		•  0.890384359682543 bayes_pls_golite062009
  • receptor binding
    		•  0.845720597560984 bayes_pls_golite062009
  • low-density lipoprotein binding
    		•  0.82178237111335 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.786172015267385 bayes_pls_golite062009
  • binding
    		•  0.549512873906854 bayes_pls_golite062009
  • serine hydrolase activity
    		•  0.527527404338 bayes_pls_golite062009
  • acylglycerol lipase activity
    		•  0.345658974420231 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  0.33062249657108 bayes_pls_golite062009
  • palmitoyl-CoA hydrolase activity
    		•  0.22473838560275 bayes_pls_golite062009
  • carboxypeptidase activity
    		•  0.0617488967154094 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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