Protein Overview: S100A9

General Information:
Name(s) found:	S100A9 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	pir\|\|B31848 calgranulin B [validated] - human [NCBI NR] gi\|7417327\|gb\|AAF62536.1\|AF237581_1 migration inhibitory factor-related protein 14 variant P [Homo sapiens] [NCBI NR] gi\|56205191\|emb\|CAI19494.1\| S100 calcium binding protein A9 [Homo sapiens] [NCBI NR] gi\|516621\|gb\|AAA68480.1\| cystic fibrosis antigen [NCBI NR] gi\|49457442\|emb\|CAG47020.1\| S100A9 [Homo sapiens] [NCBI NR] gi\|49457408\|emb\|CAG47003.1\| S100A9 [Homo sapiens] [NCBI NR] gi\|4506773\|ref\|NP_002956.1\| S100 calcium-binding protein A9 [Homo sapiens] [NCBI NR] gi\|386958\|gb\|AAA36326.1\| migration inhibitory factor-related protein 14 [NCBI NR] gi\|34771\|emb\|CAA29579.1\| unnamed protein product [Homo sapiens] [NCBI NR] gi\|29126810\|gb\|AAH47681.1\| S100 calcium binding protein A9 [Homo sapiens] [NCBI NR] gi\|225793\|prf\|\|1313351B Ca binding protein MRP14 [NCBI NR] gi\|119573719\|gb\|EAW53334.1\| S100 calcium binding protein A9 (calgranulin B), isoform CRA_a [Homo sapiens] [NCBI NR] gi\|119573718\|gb\|EAW53333.1\| S100 calcium binding protein A9 (calgranulin B), isoform CRA_a [Homo sapiens] [NCBI NR] gi\|115444\|sp\|P06702.1\|S10A9_HUMAN RecName: Full=Protein S100-A9; AltName: Full=S100 calcium-binding protein A9; AltName: Full=Calgranulin-B; AltName: Full=Migration inhibitory factor-related protein 14; Short=MRP-14; Short=P14; AltName: Full=Leukocyte L1 [NCBI NR] S100 calcium binding protein A9 [HGNC (HUGO)] Protein S100-A9 OS=Homo sapiens GN=S100A9 PE=1 SV=1 [Swiss-Prot] (P06702) Calgranulin B (Migration inhibitory factor-related protein 14) (MRP-14) (P14) (Leukocyte L1 complex heavy chain) (S100 calcium-binding protein A9) (Calprotectin L1H subunit) [Swiss-Prot] Calgranulin B [hmr_yeast5_DM3-1_pombe.fasta] S100 calcium-binding protein A9; calgranulin B [HMR_022704.fasta] S100 calcium-binding protein A9; calgranulin B; S100 calcium-binding protein A9 (calgranulin B) [071204_hmrz_cont.fasta] S100 calcium-binding protein A9 [Homo sapiens]gi\|29126810\|gb\|AAH47681.1\| S100 calcium-binding protein A9 [Homo sapiens]gi\|7417327\|gb\|AAF62536.1\| migration inhibitory factor-related protein 14 variant P [Homo sapiens]gi\|87005\|pir\|\|B31848 calgranulin B [ [nrdb_11152004_Chlamydomonas] Calgranulin B (Migration inhibitory factor-related protein 14) (MRP-14) (P14) (Leukocyte L1 complex heavy chain) (S100 calcium-binding protein A9) (Calprotectin L1H subunit) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Protein S100-A9 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_002965) S100 calcium-binding protein A9; calgranulin B [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] S100 calcium-binding protein A9 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] Tax_Id=9606 Calgranulin B [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta] S100 calcium-binding protein A9; calgranulin B; S100 calcium-binding protein A9 (calgranulin B) [Homo sapiens] [HumanGallus06162005.fasta] S100 calcium-binding protein A9; calgranulin B [Homo sapiens] [human-NCBI-042104-rand.fasta] Protein S100-A9 (S100 calcium-binding protein A9) (Calgranulin-B) (Migration inhibitory factor-related protein 14) (MRP-14) (P14) (Leukocyte L1 complex heavy chain) (Calprotectin L1H subunit) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] S100 calcium binding protein A9 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] S100 calcium binding protein A9 (calgranulin B), isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] S100A9 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] migration inhibitory factor-related protein 14 variant P [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Ca binding protein MRP14 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] MRP-14 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] cystic fibrosis antigen [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] migration inhibitory factor-related protein 14 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 CALGRANULIN B [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=S100A9 Protein S100-A9 [human-ipi-250309-contam.fasta] S100 calcium binding protein A9 (calgranulin B) [Homo sapiens] [nr-271106-contam.fasta] IPI:IPI00027462.1\|SWISS-PROT:P06702\|TREMBL:B2R4M6\|ENSEMBL:ENSP00000357727\|REFSEQ:NP_002956\|H-INV:HIT000321167\|VEGA:OTTHUMP00000015331 Tax_Id=9606 Gene_Symbol=S100A9 Protein S100-A9 [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=S100A9 Protein S100-A9 ENSG00000163220 IPI00027462 [drosphohumanreversed.fasta] protein S100-A9 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] P06702;Q6FGA1;Q9NYM0;Q9UCJ1; RecName: Full=Protein S100-A9; AltName: Full=S100 calcium-binding protein A9; AltName: Full=Calgranulin-B; AltName: Full=Migration inhibitory factor-related protein 14; AltName: Full=Leukocyte L1 complex heavy chain; AltName: Full=Calprotectin L1H subunit; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Protein S100-A9 OS=Homo sapiens GN=S100A9 [011711_HMR.fasta] IPI:IPI00027462.1\|SWISS-PROT:P06702\|TREMBL:B2R4M6;D3DV36\|ENSEMBL:ENSP00000357727\|REFSEQ:NP_002956\|H-INV:HIT000321167\|VEGA:OTTHUMP00000015331 Tax_Id=9606 Gene_Symbol=S100A9 Protein S100-A9 [ipi.HUMAN.fasta.20100406] GeneSymbol=S100A9 Synonyms=60B8AG\|CAGB\|CFAG\|CGLB\|L1AG\|LIAG\|MAC387\|MIF\|MRP14\|NIF\|P14 protein S100-A9 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] Protein S100-A9 GN=S100A9 [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	114 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MTCKMSQLER NIETIINTFH QYSVKLGHPD TLNQGEFKEL VRKDLQNFLK KENKNEKVIE 60 61 HIMEDLDTNA DKQLSFEEFI MLMARLTWAS HEKMHEGDEG PGHHHKPGLG EGTP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	gi\|14317902, gi\|...	No Comments	Cheeseman, I.M., et al. (2004)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..114]	PSI-BLAST	23.0	Calcyclin (S100)

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
S100 alpha binding	4.10422481094917	bayes_pls_golite062009
binding	3.17556402087346	bayes_pls_golite062009
cation binding	2.62077305565026	bayes_pls_golite062009
metal ion binding	2.62077305565026	bayes_pls_golite062009
ion binding	2.61312132078717	bayes_pls_golite062009
cytoskeletal protein binding	2.49140134075373	bayes_pls_golite062009
calcium-dependent protein binding	2.41193763776922	bayes_pls_golite062009
transcription regulator activity	2.23156041569913	bayes_pls_golite062009
protein binding	2.21291432166051	bayes_pls_golite062009
actin binding	2.05946574530184	bayes_pls_golite062009
structural molecule activity	2.02132683356917	bayes_pls_golite062009
nucleic acid binding	1.83723964306928	bayes_pls_golite062009
DNA binding	1.73924929536227	bayes_pls_golite062009
structural constituent of muscle	1.57184696951699	bayes_pls_golite062009
S100 beta binding	1.55177531533958	bayes_pls_golite062009
peptidase activity	1.42397628411744	bayes_pls_golite062009
calcium ion binding	1.40919295397643	bayes_pls_golite062009
motor activity	1.32027379689254	bayes_pls_golite062009
transcription repressor activity	1.24311821191924	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	1.15266823079004	bayes_pls_golite062009
microfilament motor activity	1.13222511343813	bayes_pls_golite062009
signal transducer activity	1.11607939838219	bayes_pls_golite062009
molecular transducer activity	1.11607939838219	bayes_pls_golite062009
receptor binding	0.857448001471136	bayes_pls_golite062009
endopeptidase activity	0.833336205861396	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.787740261079819	bayes_pls_golite062009
kinase activity	0.782396352346639	bayes_pls_golite062009
transporter activity	0.751717017963896	bayes_pls_golite062009
myosin binding	0.665888306029701	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.654002071540024	bayes_pls_golite062009
transmembrane transporter activity	0.573179802647827	bayes_pls_golite062009
actin filament binding	0.545758092370958	bayes_pls_golite062009
myosin heavy chain binding	0.46116030951749	bayes_pls_golite062009
hydrolase activity	0.275235036575339	bayes_pls_golite062009
actin-dependent ATPase activity	0.21797432148505	bayes_pls_golite062009
substrate-specific transporter activity	0.118606503254753	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle