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View Structure Prediction Details

Protein: S100A9
Organism: Homo sapiens
Length: 114 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for S100A9.

Description E-value Query
Range
Subject
Range
gi|73961682 - gi|73961682|ref|XP_547585.2| PREDICTED: similar to Calgranulin B (Migration inhibitory factor-relate...
5.0E-27 [1..113] [223..336]
gi|50748592 - gi|50748592|ref|XP_421316.1| PREDICTED: similar to calmodulin 1; Calmodulin 1 (phosphorylase kinase,...
1.0E-24 [1..84] [583..657]
gi|109016674 - gi|109016674|ref|XP_001108718.1| PREDICTED: similar to Protein S100-A11 (S100 calcium-binding protei...
3.0E-24 [1..101] [434..535]
gi|109504576 - gi|109504576|ref|XP_225088.3| PREDICTED: similar to S100 calcium binding protein A11 [Rattus norvegi...
8.0E-24 [3..102] [60..158]
gi|76612513 - gi|76612513|ref|XP_595126.2| PREDICTED: similar to Calgizzarin (S100 calcium-binding protein A11) (S...
8.0E-24 [5..101] [86..181]
gi|34811430, gi|... - gi|34811430|pdb|1NSH|B Chain B, Solution Structure Of Rabbit Apo-S100a11 (19 Models), gi|34811429|pd...
3.0E-23 [5..101] [3..98]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTCKMSQLER NIETIINTFH QYSVKLGHPD TLNQGEFKEL VRKDLQNFLK KENKNEKVIE  60
   61 HIMEDLDTNA DKQLSFEEFI MLMARLTWAS HEKMHEGDEG PGHHHKPGLG EGTP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.0
Match: 1irjA
Description: Calcyclin (S100)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
S100 alpha binding 4.10422481094917 bayes_pls_golite062009
binding 3.17556402087346 bayes_pls_golite062009
cation binding 2.62077305565026 bayes_pls_golite062009
metal ion binding 2.62077305565026 bayes_pls_golite062009
ion binding 2.61312132078717 bayes_pls_golite062009
cytoskeletal protein binding 2.49140134075373 bayes_pls_golite062009
calcium-dependent protein binding 2.41193763776922 bayes_pls_golite062009
transcription regulator activity 2.23156041569913 bayes_pls_golite062009
protein binding 2.21291432166051 bayes_pls_golite062009
actin binding 2.05946574530184 bayes_pls_golite062009
structural molecule activity 2.02132683356917 bayes_pls_golite062009
nucleic acid binding 1.83723964306928 bayes_pls_golite062009
DNA binding 1.73924929536227 bayes_pls_golite062009
structural constituent of muscle 1.57184696951699 bayes_pls_golite062009
S100 beta binding 1.55177531533958 bayes_pls_golite062009
peptidase activity 1.42397628411744 bayes_pls_golite062009
calcium ion binding 1.40919295397643 bayes_pls_golite062009
motor activity 1.32027379689254 bayes_pls_golite062009
transcription repressor activity 1.24311821191924 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.15266823079004 bayes_pls_golite062009
microfilament motor activity 1.13222511343813 bayes_pls_golite062009
signal transducer activity 1.11607939838219 bayes_pls_golite062009
molecular transducer activity 1.11607939838219 bayes_pls_golite062009
receptor binding 0.857448001471136 bayes_pls_golite062009
endopeptidase activity 0.833336205861396 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.787740261079819 bayes_pls_golite062009
kinase activity 0.782396352346639 bayes_pls_golite062009
transporter activity 0.751717017963896 bayes_pls_golite062009
myosin binding 0.665888306029701 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.654002071540024 bayes_pls_golite062009
transmembrane transporter activity 0.573179802647827 bayes_pls_golite062009
actin filament binding 0.545758092370958 bayes_pls_golite062009
myosin heavy chain binding 0.46116030951749 bayes_pls_golite062009
hydrolase activity 0.275235036575339 bayes_pls_golite062009
actin-dependent ATPase activity 0.21797432148505 bayes_pls_golite062009
substrate-specific transporter activity 0.118606503254753 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle