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Protein Overview: gi|92859641, gi|...

General Information:
Name(s) found: gi|92859641 [NCBI NR]
gi|119603423 [NCBI NR]
Description(s) found:
Found 17 descriptions.
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  • gi|92859641|ref|NP_004605.3| thymidine kinase 2, mitochondrial [Homo sapiens] [NCBI NR]
  • gi|119603423|gb|EAW83017.1| thymidine kinase 2, mitochondrial, isoform CRA_e [Homo sapiens] [NCBI NR]
    • Organism: Homo sapiens
    Length: 307 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRPGLFKGQA PGSRRRPTAG LAVVRADSHK KEPRASGSAR PAMLLWPLRG WAARALRCFG  60
   61 PGSRGSPASG PGPRRVQRRA WPPDKEQEKE KKSVICVEGN IASGKTTCLE FFSNATDVEV 120
  121 LTEPVSKWRN VRGHNPLGLM YHDASRWGLT LQTYVQLTML DRHTRPQVSS VRLMERSIHS 180
  181 ARYIFVENLY RSGKMPEVDY VVLSEWFDWI LRNMDVSVDL IVYLRTNPET CYQRLKKRCR 240
  241 EEEKVIPLEY LEAIHHLHEE WLIKGSLFPM AAPVLVIEAD HHMERMLELF EQNRDRILTP 300
  301 ENRKHCP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..307] PSI-BLAST 34.154902 Deoxyribonucleoside kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.0681607836408 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.92954258828893 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.09000822067541 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  1.04041661958283 bayes_pls_golite062009
  • helicase activity
    		•  1.0321619822241 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  1.00391607739958 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.913322399315129 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  0.91290128595235 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.5607032154839 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.5607032154839 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.533349084356156 bayes_pls_golite062009
  • motor activity
    		•  0.50661339105747 bayes_pls_golite062009
  • protein binding
    		•  0.378225828131122 bayes_pls_golite062009
  • DNA binding
    		•  0.376487324624615 bayes_pls_golite062009
  • CTP synthase activity
    		•  0.318856075265301 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  0.160605313145072 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.150159515184919 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.133736530545575 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  0.12351419478929 bayes_pls_golite062009
  • nucleotide binding
    		•  0.114848452385726 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.10713474095071 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.0916519414118148 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.0915913646217636 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0700789521444061 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  0.0458386180871631 bayes_pls_golite062009
  • DNA polymerase activity
    		•  4.95561462330096E-4 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.73

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle