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Protein Overview: CANX

General Information:
Name(s) found: CANX [HGNC (HUGO)]
Description(s) found:
Found 38 descriptions.
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  • calnexin [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 592 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGKWLLCML LVLGTAIVEA HDGHDDDVID IEDDLDDVIE EVEDSKPDTT APPSSPKVTY  60
   61 KAPVPTGEVY FADSFDRGTL SGWILSKAKK DDTDDEIAKY DGKWEVEEMK ESKLPGDKGL 120
  121 VLMSRAKHHA ISAKLNKPFL FDTKPLIVQY EVNFQNGIEC GGAYVKLLSK TPELNLDQFH 180
  181 DKTPYTIMFG PDKCGEDYKL HFIFRHKNPK TGIYEEKHAK RPDADLKTYF TDKKTHLYTL 240
  241 ILNPDNSFEI LVDQSVVNSG NLLNDMTPPV NPSREIEDPE DRKPEDWDER PKIPDPEAVK 300
  301 PDDWDEDAPA KIPDEEATKP EGWLDDEPEY VPDPDAEKPE DWDEDMDGEW EAPQIANPRC 360
  361 ESAPGCGVWQ RPVIDNPNYK GKWKPPMIDN PSYQGIWKPR KIPNPDFFED LEPFRMTPFS 420
  421 AIGLELWSMT SDIFFDNFII CADRRIVDDW ANDGWGLKKA ADGAAEPGVV GQMIEAAEER 480
  481 PWLWVVYILT VALPVFLVIL FCCSGKKQTS GMEYKKTDAP QPDVKEEEEE KEEEKDKGDE 540
  541 EEEGEEKLEE KQKSDAEEDG GTVSQEEEDR KPKAEEDEIL NRSPRNRKPR RE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..461] PSI-BLAST 1000.0 Calnexin
    2 View Details [462..592] FFAS03 1.06 Anabaena sensory rhodopsin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • complement component C1q binding
    		•  4.81971897425786 bayes_pls_golite062009
  • steroid hormone receptor binding
    		•  4.11346029337178 bayes_pls_golite062009
  • androgen receptor binding
    		•  3.88449123711676 bayes_pls_golite062009
  • zymosan binding
    		•  3.41405218556083 bayes_pls_golite062009
  • nuclear hormone receptor binding
    		•  3.3517714661273 bayes_pls_golite062009
  • binding
    		•  3.24845777545007 bayes_pls_golite062009
  • hormone receptor binding
    		•  3.2405597896178 bayes_pls_golite062009
  • structural molecule activity
    		•  3.0286932947016 bayes_pls_golite062009
  • unfolded protein binding
    		•  2.94586353433162 bayes_pls_golite062009
  • protein binding
    		•  2.62442480878692 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.5786381493734 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.42862869142896 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.33705817770533 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.16616430987996 bayes_pls_golite062009
  • actin binding
    		•  2.0669297251683 bayes_pls_golite062009
  • DNA binding
    		•  2.05388036301171 bayes_pls_golite062009
  • carbohydrate binding
    		•  1.90829797790335 bayes_pls_golite062009
  • sugar binding
    		•  1.89824804892868 bayes_pls_golite062009
  • receptor binding
    		•  1.70102429470678 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.69567186252006 bayes_pls_golite062009
  • signal transducer activity
    		•  1.69567186252006 bayes_pls_golite062009
  • cation binding
    		•  1.67588357161378 bayes_pls_golite062009
  • metal ion binding
    		•  1.67588357161378 bayes_pls_golite062009
  • ion binding
    		•  1.66900324045723 bayes_pls_golite062009
  • NACHT domain binding
    		•  1.53382521801494 bayes_pls_golite062009
  • integrin binding
    		•  1.36513827550387 bayes_pls_golite062009
  • transporter activity
    		•  1.29150662073327 bayes_pls_golite062009
  • chaperone binding
    		•  1.28860282614448 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  1.25720635817943 bayes_pls_golite062009
  • protein complex binding
    		•  1.23240411516711 bayes_pls_golite062009
  • RNA binding
    		•  1.22339134958708 bayes_pls_golite062009
  • heparin binding
    		•  1.15897181987617 bayes_pls_golite062009
  • transcription factor activity
    		•  1.15427978494805 bayes_pls_golite062009
  • transcription activator activity
    		•  1.11465354227601 bayes_pls_golite062009
  • polysaccharide binding
    		•  1.09475063562581 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.07075219961504 bayes_pls_golite062009
  • receptor activity
    		•  0.946182305131481 bayes_pls_golite062009
  • growth factor activity
    		•  0.850395354506359 bayes_pls_golite062009
  • pattern binding
    		•  0.83687933614214 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.814690646803591 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.801327928563072 bayes_pls_golite062009
  • mRNA binding
    		•  0.67699218614597 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.546870122670733 bayes_pls_golite062009
  • extracellular matrix structural constituent
    		•  0.52360080681204 bayes_pls_golite062009
  • calcium ion binding
    		•  0.416416901481401 bayes_pls_golite062009
  • hydrolase activity
    		•  0.374282208763552 bayes_pls_golite062009
  • monosaccharide binding
    		•  0.30021811359531 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.160855218996334 bayes_pls_golite062009
  • growth factor binding
    		•  0.0922754536898114 bayes_pls_golite062009
  • cytokine binding
    		•  0.0273545648165503 bayes_pls_golite062009
    2
    Term Confidence Notes
  • receptor activity
    		•  5.71511901997004 bayes_pls_golite062009
  • molecular transducer activity
    		•  5.61350014268597 bayes_pls_golite062009
  • signal transducer activity
    		•  5.61350014268597 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  5.58555301193414 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  5.41529591910182 bayes_pls_golite062009
  • peptide receptor activity, G-protein coupled
    		•  3.24471753253048 bayes_pls_golite062009
  • peptide receptor activity
    		•  3.23046660892783 bayes_pls_golite062009
  • neurotransmitter receptor activity
    		•  3.03590612786084 bayes_pls_golite062009
  • neurotransmitter binding
    		•  2.87541888740041 bayes_pls_golite062009
  • binding
    		•  2.71594484029277 bayes_pls_golite062009
  • retinoid binding
    		•  2.58438397457659 bayes_pls_golite062009
  • neuropeptide binding
    		•  2.5572151942717 bayes_pls_golite062009
  • neuropeptide receptor activity
    		•  2.5572151942717 bayes_pls_golite062009
  • peptide binding
    		•  2.47316566757854 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.32212946143908 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.17826584341947 bayes_pls_golite062009
  • actin binding
    		•  2.08059977933242 bayes_pls_golite062009
  • photoreceptor activity
    		•  1.92030609001248 bayes_pls_golite062009
  • G-protein coupled photoreceptor activity
    		•  1.75401574694128 bayes_pls_golite062009
  • olfactory receptor activity
    		•  1.74485554578055 bayes_pls_golite062009
  • G-protein coupled amine receptor activity
    		•  1.62445512756943 bayes_pls_golite062009
  • protein binding
    		•  1.56336697234632 bayes_pls_golite062009
  • transporter activity
    		•  1.30218997091612 bayes_pls_golite062009
  • adrenoceptor activity
    		•  1.12689604411271 bayes_pls_golite062009
  • transcription activator activity
    		•  1.11159623868222 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.0814547765264 bayes_pls_golite062009
  • receptor binding
    		•  1.001204253999 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.812148444888997 bayes_pls_golite062009
  • beta-adrenergic receptor activity
    		•  0.791607122563198 bayes_pls_golite062009
  • beta2-adrenergic receptor activity
    		•  0.791607122563198 bayes_pls_golite062009
  • norepinephrine binding
    		•  0.791607122563198 bayes_pls_golite062009
  • hydrolase activity
    		•  0.710357725030197 bayes_pls_golite062009
  • hormone receptor binding
    		•  0.595060106958951 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.557839263512813 bayes_pls_golite062009
  • amine binding
    		•  0.347034928753624 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.257270201080225 bayes_pls_golite062009
  • gated channel activity
    		•  0.118432105996465 bayes_pls_golite062009
  • cytokine binding
    		•  0.0462461949424156 bayes_pls_golite062009
  • catalytic activity
    		•  0.0258814412140621 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle