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Protein Overview: DCK

General Information:
Name(s) found: DCK [HGNC (HUGO)]
Description(s) found:
Found 33 descriptions.
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  • deoxycytidine kinase [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 260 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATPPKRSCP SFSASSEGTR IKKISIEGNI AAGKSTFVNI LKQLCEDWEV VPEPVARWCN  60
   61 VQSTQDEFEE LTMSQKNGGN VLQMMYEKPE RWSFTFQTYA CLSRIRAQLA SLNGKLKDAE 120
  121 KPVLFFERSV YSDRYIFASN LYESECMNET EWTIYQDWHD WMNNQFGQSL ELDGIIYLQA 180
  181 TPETCLHRIY LRGRNEEQGI PLEYLEKLHY KHESWLLHRT LKTNFDYLQE VPILTLDVNE 240
  241 DFKDKYESLV EKVKEFLSTL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..260] PSI-BLAST 57.39794 Deoxycytidine kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  3.72637451756504 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  3.66392587433723 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.05197579791755 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  3.0424527711731 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.0180611270204 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  2.88777247981228 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.79732178499987 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  2.77241594552543 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.68937468902218 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.6034099674264 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  2.24094813695083 bayes_pls_golite062009
  • binding
    		•  2.0681607836408 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.92954258828893 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.85943679361938 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.85937484083653 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.8521191028835 bayes_pls_golite062009
  • nucleotide binding
    		•  1.84603132945448 bayes_pls_golite062009
  • kinase activity
    		•  1.80889641165674 bayes_pls_golite062009
  • adenylate kinase activity
    		•  1.66206135528976 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.60386625568858 bayes_pls_golite062009
  • ATP binding
    		•  1.5859264197035 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.55520429131224 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.53158018507951 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.14475274823167 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.09000822067541 bayes_pls_golite062009
  • helicase activity
    		•  1.0321619822241 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  1.00391607739958 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.913322399315129 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  0.91290128595235 bayes_pls_golite062009
  • transferase activity
    		•  0.871779313294914 bayes_pls_golite062009
  • protein kinase activity
    		•  0.841952172595456 bayes_pls_golite062009
  • proton-transporting ATPase activity, rotational mechanism
    		•  0.7959427724325 bayes_pls_golite062009
  • guanylate kinase activity
    		•  0.71257393037667 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.5607032154839 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.5607032154839 bayes_pls_golite062009
  • CTP synthase activity
    		•  0.554689818807922 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.533349084356156 bayes_pls_golite062009
  • motor activity
    		•  0.50661339105747 bayes_pls_golite062009
  • cation-transporting ATPase activity
    		•  0.490497578956205 bayes_pls_golite062009
  • protein binding
    		•  0.378225828131122 bayes_pls_golite062009
  • DNA binding
    		•  0.376487324624615 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.345873656782869 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.150159515184919 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.133736530545575 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0700789521444061 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  0.0290859525230198 bayes_pls_golite062009
  • DNA polymerase activity
    		•  4.95561462330096E-4 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle