Protein Overview: him-1

General Information:
Name(s) found:	him-1 / CE39925 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00001860 locus:him-1 status:Confirmed UniProt:Q2A957 protein_id:CCD69826.1 [WormBase] gi\|89179554\|gb\|ABD63228.1\| High incidence of males (increased x chromosome loss) protein 1, isoform b [Caenorhabditis elegans] [NCBI NR] gi\|115532288\|ref\|NP_001040659.1\| High Incidence of Males (increased X chromosome loss) family member (him-1) [Caenorhabditis elegans] [NCBI NR] CE39925 WBGene00001860 locus:him-1 status:Confirmed UniProt:Q2A957_CAEEL protein_id:ABD63228.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE39925 WBGene00001860 locus:him-1 status:Confirmed UniProt:Q2A957_CAEEL protein_id:ABD63228.1\| [wormORF-contam.fasta] CE39925 WBGene00001860 locus:him-1 status:Confirmed TR:Q2A957 protein_id:ABD63228.1 [wormpep160-contam.fasta] High incidence of males (increased x chromosome loss) protein 1, isoform b [Caenorhabditis elegans] [nr-271106-contam.fasta] High Incidence of Males (increased X chromosome loss) family member (him-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE39925 WBGene00001860 locus:him-1 status:Confirmed UniProt:Q2A957 protein_id:ABD63228.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE39925 WBGene00001860 locus:him-1 status:Confirmed UniProt:Q2A957 protein_id:CCD69826.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE39925 WBGene00001860 locus:him-1 status:Confirmed UniProt:O01789 protein_id:CCD69826.1 Structural maintenance of chromosomes protein 1 [c_elegans-PRJNA13758-WS250-ecoli-contam.fasta] Isoform of O01789, Isoform b of Structural maintenance of chromosomes protein 1 OS=Caenorhabditis elegans GN=him-1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	140 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] nuclear chromatin [IDA] cohesin complex [ISS] chromosome [IEA]
Biological Process:	embryonic development [IMP] DNA repair [IEA] response to X-ray [IMP] hermaphrodite genitalia development [IMP] embryonic development ending in birth or egg hatching [IMP ] mitotic sister chromatid cohesion [ISS] chromosome segregation [IMP] response to UV [IMP] DNA metabolic process [IEA] reproduction [IMP] growth [IMP] locomotory behavior [IMP] chromosome organization [IEA] nematode larval development [IMP]
Molecular Function:	DNA binding [IDA] ATP binding [IEA] protein binding [IDA][IEA] single-stranded DNA binding [IEA]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MEEPYLDGIQ YNCVAPGKRF RPMDNLSGGE KTIAALALLF AVHGRNPAPF FVLDEIDAAL 60 61 DNTNIGKVAS YICESAREHM QIIVISLKEE FYNKADSLIG IFPYPAACTT SGVLTFDLTR 120 121 FKQIGLNEMT ENPPTPSIAT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

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No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..140]	PSI-BLAST	11.0	Sc Smc1hd:Scc1-C complex, ATPgS

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.86

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle