Protein Overview: SOX9

General Information:
Name(s) found:	SOX9 [HGNC (HUGO)]
Description(s) found: Found 38 descriptions. SHOW ALL	SRY (sex determining region Y)-box 9 [HGNC (HUGO)]
Organism:	Homo sapiens
Length:	509 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLLDPFMKM TDEQEKGLSG APSPTMSEDS AGSPCPSGSG SDTENTRPQE NTFPKGEPDL  60
   61 KKESEEDKFP VCIREAVSQV LKGYDWTLVP MPVRVNGSSK NKPHVKRPMN AFMVWAQAAR 120
  121 RKLADQYPHL HNAELSKTLG KLWRLLNESE KRPFVEEAER LRVQHKKDHP DYKYQPRRRK 180
  181 SVKNGQAEAE EATEQTHISP NAIFKALQAD SPHSSSGMSE VHSPGEHSGQ SQGPPTPPTT 240
  241 PKTDVQPGKA DLKREGRPLP EGGRQPPIDF RDVDIGELSS DVISNIETFD VNEFDQYLPP 300
  301 NGHPGVPATH GQVTYTGSYG ISSTAATPAS AGHVWMSKQQ APPPPPQQPP QAPPAPQAPP 360
  361 QPQAAPPQQP AAPPQQPQAH TLTTLSSEPG QSQRTHIKTE QLSPSHYSEQ QQHSPQQIAY 420
  421 SPFNLPHYSP SYPPITRSQY DYTDHQNSSS YYSHAAGQGT GLYSTFTYMN PAQRPMYTPI 480
  481 ADTSGVPSIP QTHSPQHWEQ PVYTQLTRP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..100]	deduced	N/A	No confident structure predictions are available.
2	View Details	[101..260]	PSI-BLAST	19.522879	No description for 2gzkA was found.
3	View Details	[261..339]	deduced	N/A	No confident structure predictions are available.
4	View Details	[340..509]	MSA	8.212997	View MSA. No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

Term	Confidence	Notes
DNA binding	5.15324651287773	bayes_pls_golite062009
nucleic acid binding	5.01228762819617	bayes_pls_golite062009
transcription regulator activity	4.9607192917135	bayes_pls_golite062009
sequence-specific DNA binding	4.06355503548774	bayes_pls_golite062009
transcription factor activity	3.82658263870186	bayes_pls_golite062009
binding	3.6211482127468	bayes_pls_golite062009
transcription repressor activity	3.17018042329608	bayes_pls_golite062009
transcription activator activity	2.95665802871704	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.75319687398598	bayes_pls_golite062009
protein binding	2.18211240370246	bayes_pls_golite062009
chromatin binding	1.64428658020027	bayes_pls_golite062009
transcription factor binding	1.10315330167937	bayes_pls_golite062009
DNA bending activity	0.87985209274756	bayes_pls_golite062009
specific transcriptional repressor activity	0.4255419067266	bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding	0.261169200304829	bayes_pls_golite062009

3

No functions predicted.

4

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle