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Protein Overview: ELL

General Information:
Name(s) found: ELL [HGNC (HUGO)]
Description(s) found:
Found 32 descriptions.
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  • elongation factor RNA polymerase II [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 621 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALKEDRSY GLSCGRVSDG SKVSVFHVKL TDSALRAFES YRARQDSVSL RPSIRFQGSQ  60
   61 GHISIPQPDC PAEARTFSFY LSNIGRDNPQ GSFDCIQQYV SSHGEVHLDC LGSIQDKITV 120
  121 CATDDSYQKA RQSMAQAEEE TRSRSAIVIK AGGRYLGKKV QFRKPAPGAT DAVPSRKRAT 180
  181 PINLASAIRK SGASAVSGGS GVSQRPFRDR VLHLLALRPY RKAELLLRLQ KDGLTQADKD 240
  241 ALDGLLQQVA NMSAKDGTCT LQDCMYKDVQ KDWPGYSEGD QQLLKRVLVR KLCQPQSTGS 300
  301 LLGDPAASSP PGERGRSASP PQKRLQPPDF IDPLANKKPR ISHFTQRAQP AVNGKLGVPN 360
  361 GREALLPTPG PPASTDTLSS STHLPPRLEP PRAHDPLADV SNDLGHSGRD CEHGEAAAPA 420
  421 PTVRLGLPLL TDCAQPSRPH GSPSRSKPKK KSKKHKDKER AAEDKPRAQL PDCAPATHAT 480
  481 PGAPADTPGL NGTCSVSSVP TSTSETPDYL LKYAAISSSE QRQSYKNDFN AEYSEYRDLH 540
  541 ARIERITRRF TQLDAQLRQL SQGSEEYETT RGQILQEYRK IKKTNTNYSQ EKHRCEYLHS 600
  601 KLAHIKRLIA EYDQRQLQAW P

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..131] MSA 1.143968 View MSA. No confident structure predictions are available.
    2 View Details [132..290] FFAS03 3.55 No description for 2doaA was found.
    3 View Details [291..399] MSA 4.21499 View MSA. No confident structure predictions are available.
    4 View Details [400..491] MSA 3.209991 View MSA. No confident structure predictions are available.
    5 View Details [492..621] PSI-BLAST 31.221849 crystal structure of the cytoplasmic distal C-terminal domain of occludin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.23858959608048 bayes_pls_golite062009
  • DNA binding
    		•  4.54024488199476 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.30331577005505 bayes_pls_golite062009
  • binding
    		•  3.89976494610525 bayes_pls_golite062009
  • transcription factor activity
    		•  3.82269332595313 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.41045867230388 bayes_pls_golite062009
  • transcription activator activity
    		•  2.13702350917359 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.12567455635303 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.9708626903609 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  1.75305601393584 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.976708325140011 bayes_pls_golite062009
  • transcription factor binding
    		•  0.752335897765285 bayes_pls_golite062009
  • protein binding
    		•  0.749376520208656 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.490809930581315 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle