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Protein Overview: EIF3E

General Information:
Name(s) found: EIF3E [HGNC (HUGO)]
Description(s) found:
Found 47 descriptions.
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  • eukaryotic translation initiation factor 3, subunit E [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 445 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEYDLTTRI AHFLDRHLVF PLLEFLSVKE IYNEKELLQG KLDLLSDTNM VDFAMDVYKN  60
   61 LYSDDIPHAL REKRTTVVAQ LKQLQAETEP IVKMFEDPET TRQMQSTRDG RMLFDYLADK 120
  121 HGFRQEYLDT LYRYAKFQYE CGNYSGAAEY LYFFRVLVPA TDRNALSSLW GKLASEILMQ 180
  181 NWDAAMEDLT RLKETIDNNS VSSPLQSLQQ RTWLIHWSLF VFFNHPKGRD NIIDLFLYQP 240
  241 QYLNAIQTMC PHILRYLTTA VITNKDVRKR RQVLKDLVKV IQQESYTYKD PITEFVECLY 300
  301 VNFDFDGAQK KLRECESVLV NDFFLVACLE DFIENARLFI FETFCRIHQC ISINMLADKL 360
  361 NMTPEEAERW IVNLIRNARL DAKIDSKLGH VVMGNNAVSP YQQVIEKTKS LSFRSQMLAM 420
  421 NIEKKLNQNS RSEAPNWATQ DSGFY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..130] Pfam 81.0 No description for PF09440.1 was found. No confident structure predictions are available.
    2 View Details [131..302] MSA 2.195978 View MSA. No confident structure predictions are available.
    3 View Details [303..445] FFAS03 2.74 Solution structure of the PCI domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  4.83417082121324 bayes_pls_golite062009
  • DNA binding
    		•  4.45307043231712 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.31598146918736 bayes_pls_golite062009
  • transcription factor activity
    		•  3.74401182888821 bayes_pls_golite062009
  • binding
    		•  3.37660003833383 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.974370828939 bayes_pls_golite062009
  • transcription activator activity
    		•  2.95095409497726 bayes_pls_golite062009
  • structural molecule activity
    		•  2.72616711594099 bayes_pls_golite062009
  • RNA binding
    		•  2.57915942568691 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.13497236448364 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.87251560747782 bayes_pls_golite062009
  • protein binding
    		•  1.77689943618029 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.30087087585117 bayes_pls_golite062009
  • mRNA binding
    		•  1.03970887182906 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.01831614309793 bayes_pls_golite062009
  • transcription factor binding
    		•  0.675707749846405 bayes_pls_golite062009
  • hydrolase activity
    		•  0.20695163916851 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.142921675412538 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.124542865343065 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle