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Protein Overview: gi|2224593

General Information:
Name(s) found: gi|2224593 [NCBI NR]
Description(s) found:
Found 3 descriptions.
SHOW ALL
  • gi|2224593|dbj|BAA20784.1| KIAA0326 [Homo sapiens] [NCBI NR]
    • Organism: Homo sapiens
    Length: 927 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RVLSLESPLE KDPRVLGAQS VPRGRALKGL SPLGLDSAFR LFPDPRAGPW NTAVLSSGME  60
   61 PETALWGPDL QGPEQSPNDA HRGAESENEE ESPRQESSGE EIIMGDPAQS PESKDSTEMS 120
  121 LERSSQDPSV PQNPPTPLGH SNPLDHQIPL DPPAPEVVPT PSDWTKACEA SWQWGALTTW 180
  181 NSPPVVPANE PSLRELVQGR PAGAEKPYIC NECGKSFSQW SKLLRHQRIH TGERPNTCSE 240
  241 CGKSFTQSSH LVQHQRTHTG EKPYKCPDCG KCFSWSSNLV QHQRTHTGEK PYKCTECEKA 300
  301 FTQSTNLIKH QRSHTGEKPY KCGECRRAFY RSSDLIQHQA THTGEKPYKC PECGKRFGQN 360
  361 HNLLKHQKIH AGEKPYRCTE CGKSFIQSSE LTQHQRTHTG EKPYECLECG KSFGHSSTLI 420
  421 KHQRTHLRED PFKCPVCGKT FTLSATLLRH QRTHTGERPY KCPECGKSFS VSSNLINHQR 480
  481 IHRGERPYIC ADCGKSFIMS STLIRHQRIH TGEKPYKCSD CGKSFIRSSH LIQHRRTHTG 540
  541 EKPYKCPECG KSFSQSSNLI THVRTHMDEN LFVCSDCGKA FLEAHELEQH RVIHERGKTP 600
  601 ARRAQGDSLL GLGDPSLLTP PPGAKPHKCL VCGKGFNDEG IFMQHQRIHI GENPYKNADG 660
  661 LIAHAAPKPP QLRSPRLPFR GNSYPGAAEG RAEAPGQPLK PPEGQEGFSQ RRGLLSSKTY 720
  721 ICSHCGESFL DRSVLLQHQL THGNEKPFLF PDYRIGLGEG AGPSPFLSGK PFKCPECKQS 780
  781 FGLSSELLLH QKVHAGGKSS QKSPELGKSS SVLLEHLRSP LGARPYRCSD CRASFLDRVA 840
  841 LTRHQETHTQ EKPPNPEDPP PEAVTLSTDQ EGEGETPTPT ESSSHGEGQN PKTLVEEKPY 900
  901 LCPECGAGFT EVAALLLHRS CHPGVSL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..61] MSA 3.298995 View MSA. No confident structure predictions are available.
    2 View Details [62..163] deduced N/A No confident structure predictions are available.
    3 View Details [164..372] FFAS03 6.9 Transcription factor IIIA, TFIIIA
    4 View Details [373..570] PSI-BLAST 35.69897 No description for 2i13A was found.
    5 View Details [571..680] FFAS03 6.4 No description for 2i13A was found.
    6 View Details [681..927] PSI-BLAST 10.522879 Transcription factor IIIA, TFIIIA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  4.47951889934838 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.35187767955595 bayes_pls_golite062009
  • DNA binding
    		•  4.31051339571017 bayes_pls_golite062009
  • transcription factor activity
    		•  3.28758716579796 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.07956158665183 bayes_pls_golite062009
  • binding
    		•  2.99742524370422 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.96255357208943 bayes_pls_golite062009
  • protein binding
    		•  2.00293511941456 bayes_pls_golite062009
  • transcription activator activity
    		•  1.97757778483124 bayes_pls_golite062009
  • chromatin binding
    		•  1.91511881662436 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.35857850481346 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.33097016250582 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.31750643711614 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.26862497534835 bayes_pls_golite062009
  • transcription factor binding
    		•  1.23738346570539 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.16887811832337 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  1.00239065862819 bayes_pls_golite062009
  • tubulin binding
    		•  0.842454828267342 bayes_pls_golite062009
  • microtubule binding
    		•  0.72790523767509 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.627794176881836 bayes_pls_golite062009
  • catalytic activity
    		•  0.263007611601737 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6
    Term Confidence Notes
  • transcription regulator activity
    		•  4.70988788192472 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.58713908116892 bayes_pls_golite062009
  • DNA binding
    		•  4.56219307357342 bayes_pls_golite062009
  • transcription factor activity
    		•  3.50954949535763 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.27542149084008 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.22082323675675 bayes_pls_golite062009
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • transcription activator activity
    		•  2.19952417915035 bayes_pls_golite062009
  • chromatin binding
    		•  2.18464662431232 bayes_pls_golite062009
  • protein binding
    		•  2.05530362750351 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.63161912031789 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.48624530884061 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.42975942698743 bayes_pls_golite062009
  • transcription factor binding
    		•  1.39608963544799 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.34049786451995 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.31662328614288 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  1.18599503594288 bayes_pls_golite062009
  • tubulin binding
    		•  0.885027017225994 bayes_pls_golite062009
  • microtubule binding
    		•  0.780072635419707 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.77874411480713 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle