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Protein Overview: gi|119596761, gi...

General Information:
Name(s) found: gi|5748522 [NCBI NR]
gi|28559061 [NCBI NR]
gi|119596761 [NCBI NR]
Description(s) found:
Found 23 descriptions.
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  • gi|5748522|emb|CAB53071.1| DNA (cytosine-5-)-methyltransferase 3 beta [Homo sapiens] [NCBI NR]
  • gi|28559061|ref|NP_787044.1| DNA cytosine-5 methyltransferase 3 beta isoform 2 [Homo sapiens] [NCBI NR]
  • gi|119596761|gb|EAW76355.1| DNA (cytosine-5-)-methyltransferase 3 beta, isoform CRA_d [Homo sapiens] [NCBI NR]
    • Organism: Homo sapiens
    Length: 833 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKGDTRHLNG EEDAGGREDS ILVNGACSDQ SSDSPPILEA IRTPEIRGRR SSSRLSKREV  60
   61 SSLLSYTQDL TGDGDGEDGD GSDTPVMPKL FRETRTRSES PAVRTRNNNS VSSRERHRPS 120
  121 PRSTRGRQGR NHVDESPVEF PATRSLRRRA TASAGTPWPS PPSSYLTIDL TDDTEDTHGT 180
  181 PQSSSTPYAR LAQDSQQGGM ESPQVEADSG DGDSSEYQDG KEFGIGDLVW GKIKGFSWWP 240
  241 AMVVSWKATS KRQAMSGMRW VQWFGDGKFS EVSADKLVAL GLFSQHFNLA TFNKLVSYRK 300
  301 AMYHALEKAR VRAGKTFPSS PGDSLEDQLK PMLEWAHGGF KPTGIEGLKP NNTQPENKTR 360
  361 RRTADDSATS DYCPAPKRLK TNCYNNGKDR GDEDQSREQM ASDVANNKSS LEDGCLSCGR 420
  421 KNPVSFHPLF EGGLCQTCRD RFLELFYMYD DDGYQSYCTV CCEGRELLLC SNTSCCRCFC 480
  481 VECLEVLVGT GTAAEAKLQE PWSCYMCLPQ RCHGVLRRRK DWNVRLQAFF TSDTGLEYEA 540
  541 PKLYPAIPAA RRRPIRVLSL FDGIATGYLV LKELGIKVGK YVASEVCEES IAVGTVKHEG 600
  601 NIKYVNDVRN ITKKNIEEWG PFDLVIGGSP CNDLSNVNPA RKGLYEGTGR LFFEFYHLLN 660
  661 YSRPKEGDDR PFFWMFENVV AMKVGDKRDI SRFLECNPVM IDAIKVSAAH RARYFWGNLP 720
  721 GMNRPVIASK NDKLELQDCL EYNRIAKLKK VQTITTKSNS IKQGKNQLFP VVMNGKEDVL 780
  781 WCTELERIFG FPVHYTDVSN MGRGARQKLL GRSWSVPVIR HLFAPLKDYF ACE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..201] MSA 13.288996 View MSA. No confident structure predictions are available.
    2 View Details [202..391] PSI-BLAST 28.0 DNA methyltransferase DNMT3B
    3 View Details [392..722] PSI-BLAST 78.69897 No description for 2pv0B was found.
    4 View Details [723..833] PSI-BLAST 60.154902 DNA methylase HaeIII

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
    		•  7.32955324136098 bayes_pls_golite062009
  • DNA (cytosine-5-)-methyltransferase activity
    		•  5.05440120599055 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  4.57248514274229 bayes_pls_golite062009
  • methylated histone residue binding
    		•  3.99360930536438 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  3.58146193288239 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.34067645460735 bayes_pls_golite062009
  • unmethylated CpG binding
    		•  3.31276815221906 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.21000367413295 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  3.0892691305178 bayes_pls_golite062009
  • binding
    		•  3.03932294945523 bayes_pls_golite062009
  • protein binding
    		•  2.81959915474598 bayes_pls_golite062009
  • histone binding
    		•  2.53075587257882 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  2.42481282100188 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  2.42481282100188 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  2.42481282100188 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.39870293911569 bayes_pls_golite062009
  • DNA binding
    		•  2.38812251097879 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  2.35081504375623 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  2.18489564426455 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.65392797012899 bayes_pls_golite062009
  • transcription factor binding
    		•  1.49481919243505 bayes_pls_golite062009
  • methyltransferase activity
    		•  1.45012620929102 bayes_pls_golite062009
  • transcription factor activity
    		•  1.41108699101741 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  1.37282797213354 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.36802409360413 bayes_pls_golite062009
  • chromatin binding
    		•  0.8915883636553 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K36 specific)
    		•  0.668498662418847 bayes_pls_golite062009
  • retinoid X receptor binding
    		•  0.56323697625529 bayes_pls_golite062009
  • retinoic acid receptor binding
    		•  0.52209845652926 bayes_pls_golite062009
  • transcription activator activity
    		•  0.262486595331603 bayes_pls_golite062009
  • histone methyltransferase activity (H4-K20 specific)
    		•  0.227288548958153 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.141502107934206 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle