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Protein Overview: ID2

General Information:
Name(s) found: ID2 [HGNC (HUGO)]
Description(s) found:
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  • gi|729806|sp|Q02363.1|ID2_HUMAN RecName: Full=DNA-binding protein inhibitor ID-2; AltName: Full=Inhibitor of DNA binding 2 [NCBI NR]
  • gi|62822261|gb|AAY14810.1| unknown [Homo sapiens] [NCBI NR]
  • gi|54632181|gb|AAV35470.1| cell growth-inhibiting gene 8 [Homo sapiens] [NCBI NR]
  • gi|471126|dbj|BAA02990.1| Id-2H [Homo sapiens] [NCBI NR]
  • gi|31982933|ref|NP_002157.2| inhibitor of DNA binding 2 [Homo sapiens] [NCBI NR]
  • pir||A40227 transcription repressor Id-2 - human [NCBI NR]
  • gi|21040395|gb|AAH30639.1| Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein [Homo sapiens] [NCBI NR]
  • gi|189065204|dbj|BAG34927.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|119621424|gb|EAX01019.1| inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119621423|gb|EAX01018.1| inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, isoform CRA_a [Homo sapiens] [NCBI NR]
  • inhibitor of DNA binding 2, dominant negative helix-loop-helix protein [HGNC (HUGO)]
  • DNA-binding protein inhibitor ID-2 OS=Homo sapiens GN=ID2 PE=1 SV=1 [Swiss-Prot]
  • DNA-binding protein inhibitor ID-2 [hmr_yeast5_DM3-1_pombe.fasta]
  • inhibitor of DNA binding 2; inhibitor of differentiation 2; DNA-binding protein inhibitor ID2; helix-loop-helix protein ID2 [HMR_022704.fasta]
  • inhibitor of DNA binding 2 [Homo sapiens]gi|21040395|gb|AAH30639.1| Inhibitor of DNA binding 2 [Homo sapiens]gi|471126|dbj|BAA02990.1| Id-2H [Homo sapiens]gi|729806|sp|Q02363|ID2_HUMAN DNA-binding protein inhibitor ID-2gi|284167|pir||A40227 transcript [nrdb_11152004_Chlamydomonas]
  • DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 DNA-binding protein inhibitor ID-2 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • inhibitor of DNA binding 2 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • inhibitor of DNA binding 2; inhibitor of differentiation 2; DNA-binding protein inhibitor ID2; helix-loop-helix protein ID2 [Homo sapiens] [HumanGallus06162005.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • cell growth-inhibiting gene 8 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unknown [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Id-2H [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 DNA-BINDING PROTEIN INHIBITOR ID-2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=ID2 DNA-binding protein inhibitor ID-2 [human-ipi-250309-contam.fasta]
  • IPI:IPI00294210.3|SWISS-PROT:Q02363|TREMBL:Q53H99;Q53T66|ENSEMBL:ENSP00000234091;ENSP00000379585;ENSP00000385465|REFSEQ:NP_002157|H-INV:HIT000302233|VEGA:OTTHUMP00000140258;OTTHUMP00000200297 Tax_Id=9606 Gene_Symbol=ID2 DNA-binding protein inhibitor ID-2 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=ID2 DNA-binding protein inhibitor ID-2 ENSG00000115738 IPI00294210 [drosphohumanreversed.fasta]
  • DNA-binding protein inhibitor ID-2 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q02363; RecName: Full=DNA-binding protein inhibitor ID-2; AltName: Full=Inhibitor of DNA binding 2; AltName: Full=Class B basic helix-loop-helix protein 26; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • DNA-binding protein inhibitor ID-2 OS=Homo sapiens GN=ID2 [011711_HMR.fasta]
  • GeneSymbol=ID2 Synonyms=GIG8|ID2A|ID2H|MGC26389|bHLHb26 DNA-binding protein inhibitor ID-2 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • DNA-binding protein inhibitor ID-2 GN=ID2 [Doctor+uniprot-HUMAN-120911.fasta]
  • Cell growth-inhibiting gene 8 OS=Homo sapiens GN=ID2 PE=2 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 134 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS  60
   61 KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF 120
  121 PSELMSNDSK ALCG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..134] PSI-BLAST 14.39794 Myc prot-oncogene protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  5.38658950816179 bayes_pls_golite062009
  • DNA binding
    		•  5.18654839258297 bayes_pls_golite062009
  • nucleic acid binding
    		•  5.05768805749761 bayes_pls_golite062009
  • transcription factor activity
    		•  4.78039531631248 bayes_pls_golite062009
  • binding
    		•  3.81829206350975 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.39500382187264 bayes_pls_golite062009
  • protein binding
    		•  2.64975291677725 bayes_pls_golite062009
  • transcription factor binding
    		•  2.61163564741984 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.58751248599889 bayes_pls_golite062009
  • transcription activator activity
    		•  2.5495467409976 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  2.42306484786159 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.31910036997977 bayes_pls_golite062009
  • transcription corepressor activity
    		•  2.03674713048499 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.52770895937238 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.07771706364343 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.93846047598021 bayes_pls_golite062009
  • promoter binding
    		•  0.8576109846276 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.53175615551166 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.3513586903977 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.20674648626116 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle