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Protein Overview: AQP3

General Information:
Name(s) found: AQP3 [HGNC (HUGO)]
Description(s) found:
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  • gi|67515413|gb|AAY68214.1| aquaporin 3 [Homo sapiens] [NCBI NR]
  • gi|55959112|emb|CAI13311.1| aquaporin 3 (Gill blood group) [Homo sapiens] [NCBI NR]
  • gi|49456935|emb|CAG46788.1| AQP3 [Homo sapiens] [NCBI NR]
  • gi|4826645|ref|NP_004916.1| aquaporin 3 [Homo sapiens] [NCBI NR]
  • gi|30583237|gb|AAP35863.1| aquaporin 3 [Homo sapiens] [NCBI NR]
  • gi|2497938|sp|Q92482.2|AQP3_HUMAN RecName: Full=Aquaporin-3; Short=AQP-3 [NCBI NR]
  • gi|189055129|dbj|BAG38113.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|1854374|dbj|BAA19237.1| aquaporin 3 [Homo sapiens] [NCBI NR]
  • gi|15488871|gb|AAH13566.1| Aquaporin 3 (Gill blood group) [Homo sapiens] [NCBI NR]
  • gi|119578908|gb|EAW58504.1| aquaporin 3 (Gill blood group), isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119578904|gb|EAW58500.1| aquaporin 3 (Gill blood group), isoform CRA_a [Homo sapiens] [NCBI NR]
  • aquaporin 3 (Gill blood group) [HGNC (HUGO)]
  • Aquaporin-3 OS=Homo sapiens GN=AQP3 PE=2 SV=2 [Swiss-Prot]
  • Splice isoform 1 of Q92482 [hmr_yeast5_DM3-1_pombe.fasta]
  • aquaporin 3 [HMR_022704.fasta]
  • aquaporin 3 [Homo sapiens]gi|30583237|gb|AAP35863.1| aquaporin 3 [Homo sapiens]gi|15488871|gb|AAH13566.1| Aquaporin 3 [Homo sapiens]gi|2497938|sp|Q92482|AQP3_HUMAN Aquaporin 3gi|49456935|emb|CAG46788.1| AQP3 [Homo sapiens]gi|1854374|dbj|BAA19237.1| a [nrdb_11152004_Chlamydomonas]
  • Aquaporin 3 [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Aquaporin-3 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_004925) aquaporin 3 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • aquaporin 3 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Aquaporin-3 (AQP-3) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • aquaporin 3 (Gill blood group) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • aquaporin 3 (Gill blood group), isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Aquaporin 3 (Gill blood group) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • AQP3 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of Aquaporin-3 [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 1 OF AQUAPORIN 3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=AQP3 Isoform 1 of Aquaporin-3 [human-ipi-250309-contam.fasta]
  • IPI:IPI00021558.4|SWISS-PROT:Q92482-1|TREMBL:A8K843;B2RE16;Q6FGT2|ENSEMBL:ENSP00000297991|REFSEQ:NP_004916|H-INV:HIT000278303|VEGA:OTTHUMP00000021206 Tax_Id=9606 Gene_Symbol=AQP3 Isoform 1 of Aquaporin-3 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=AQP3 Isoform 1 of Aquaporin-3 ENSG00000165272 IPI00514225 IPI00021558 IPI00216545 [drosphohumanreversed.fasta]
  • aquaporin-3 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q92482;B2RE16;O00108;Q6FGW6; RecName: Full=Aquaporin-3; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Aquaporin-3 OS=Homo sapiens GN=AQP3 [011711_HMR.fasta]
  • IPI:IPI00021558.4|SWISS-PROT:Q92482-1|TREMBL:A8K843;D3DRL3;Q6FGT2|ENSEMBL:ENSP00000297991|REFSEQ:NP_004916|H-INV:HIT000278303|VEGA:OTTHUMP00000021206 Tax_Id=9606 Gene_Symbol=AQP3 Isoform 1 of Aquaporin-3 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=AQP3 Synonyms=GIL aquaporin-3 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00021558.4|SWISS-PROT:Q92482-1|ENSEMBL:ENSP00000297991|REFSEQ:NP_004916|H-INV:HIT000278303|VEGA:OTTHUMP00000021206 Tax_Id=9606 Gene_Symbol=AQP3 Isoform 1 of Aquaporin-3 [ipi.HUMAN.20110912.fasta]
  • Aquaporin-3 GN=AQP3 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 292 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRQKELVSR CGEMLHIRYR LLRQALAECL GTLILVMFGC GSVAQVVLSR GTHGGFLTIN  60
   61 LAFGFAVTLG ILIAGQVSGA HLNPAVTFAM CFLAREPWIK LPIYTLAQTL GAFLGAGIVF 120
  121 GLYYDAIWHF ADNQLFVSGP NGTAGIFATY PSGHLDMING FFDQFIGTAS LIVCVLAIVD 180
  181 PYNNPVPRGL EAFTVGLVVL VIGTSMGFNS GYAVNPARDF GPRLFTALAG WGSAVFTTGQ 240
  241 HWWWVPIVSP LLGSIAGVFV YQLMIGCHLE QPPPSNEEEN VKLAHVKHKE QI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..292] PSI-BLAST 59.69897 Glycerol uptake facilitator protein GlpF

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • water transmembrane transporter activity
    		•  10.3414560257964 bayes_pls_golite062009
  • water channel activity
    		•  10.2169080705067 bayes_pls_golite062009
  • amide transmembrane transporter activity
    		•  8.22334514934522 bayes_pls_golite062009
  • urea channel activity
    		•  8.22334514934522 bayes_pls_golite062009
  • urea transmembrane transporter activity
    		•  8.22334514934522 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  6.84984722645819 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  6.65010837320829 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  6.65010837320829 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  6.49777654791183 bayes_pls_golite062009
  • channel activity
    		•  6.47484344601535 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  6.47484344601535 bayes_pls_golite062009
  • transporter activity
    		•  5.23077472964938 bayes_pls_golite062009
  • pyrimidine transmembrane transporter activity
    		•  5.22583580934587 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  5.06520190871345 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  4.83314424546299 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.7450921192571 bayes_pls_golite062009
  • glycerol channel activity
    		•  4.65460547189577 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.89377210429696 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity
    		•  2.87423888562609 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.66719193997824 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.14052261196782 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  1.57078059027065 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  1.57017437613762 bayes_pls_golite062009
  • cation channel activity
    		•  1.51074107596522 bayes_pls_golite062009
  • ion channel activity
    		•  1.40084800732756 bayes_pls_golite062009
  • nucleobase transmembrane transporter activity
    		•  1.34339324336864 bayes_pls_golite062009
  • purine transmembrane transporter activity
    		•  1.34339324336864 bayes_pls_golite062009
  • binding
    		•  1.29002883661034 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  1.16825682067665 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.315342449421593 bayes_pls_golite062009
  • protein binding
    		•  0.279304481542405 bayes_pls_golite062009
  • structural molecule activity
    		•  0.180281371901848 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle