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Protein Overview: SMNDC1

General Information:
Name(s) found: SMNDC1 [HGNC (HUGO)]
Description(s) found:
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  • gi|55959458|emb|CAI15482.1| survival motor neuron domain containing 1 [Homo sapiens] [NCBI NR]
  • gi|5032113|ref|NP_005862.1| survival motor neuron domain containing 1 [Homo sapiens] [NCBI NR]
  • gi|3986748|gb|AAC84148.1| splicing factor [Homo sapiens] [NCBI NR]
  • gi|3746842|gb|AAC64086.1| 30kDa splicing factor; SPF 30 [Homo sapiens] [NCBI NR]
  • gi|37087924|sp|O75940.1|SPF30_HUMAN RecName: Full=Survival of motor neuron-related-splicing factor 30; AltName: Full=SMN-related protein; AltName: Full=30 kDa splicing factor SMNrp; AltName: Full=Survival motor neuron domain-containing protein 1 [NCBI NR]
  • gi|15029993|gb|AAH11234.1| Survival motor neuron domain containing 1 [Homo sapiens] [NCBI NR]
  • gi|119569949|gb|EAW49564.1| survival motor neuron domain containing 1, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119569947|gb|EAW49562.1| survival motor neuron domain containing 1, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119569946|gb|EAW49561.1| survival motor neuron domain containing 1, isoform CRA_a [Homo sapiens] [NCBI NR]
  • survival motor neuron domain containing 1 [HGNC (HUGO)]
  • Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens GN=SMNDC1 PE=1 SV=1 [Swiss-Prot]
  • (O75940) Survival of motor neuron-related splicing factor 30 (SMN-related protein) (30 kDa splicing factor SMNrp) (Survival motor neuron domain containing protein 1) [Swiss-Prot]
  • 30 kDa splicing factor [hmr_yeast5_DM3-1_pombe.fasta]
  • survival motor neuron domain containing 1; splicing factor 30, survival of motor neuron-related [HMR_022704.fasta]
  • survival motor neuron domain containing 1 [Homo sapiens]gi|15029993|gb|AAH11234.1| Survival motor neuron domain containing 1 [Homo sapiens]gi|37087924|sp|O75940|SF30_HUMAN Survival of motor neuron-related splicing factor 30 (SMN-related protein) (30 kDa [nrdb_11152004_Chlamydomonas]
  • Survival of motor neuron-related splicing factor 30 (SMN-related protein) (30 kDa splicing factor SMNrp) (Survival motor neuron domain containing protein 1) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Survival of motor neuron-related splicing factor 30 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_005871) splicing factor 30, survival of motor neuron-related [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • survival motor neuron domain containing 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • survival motor neuron domain containing 1; splicing factor 30, survival of motor neuron-related [Homo sapiens] [HumanGallus06162005.fasta]
  • Survival of motor neuron-related-splicing factor 30 (SMN-related protein) (30 kDa splicing factor SMNrp) (Survival motor neuron domain-containing protein 1) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • survival motor neuron domain containing 1, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Survival motor neuron domain containing 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • splicing factor [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • 30kDa splicing factor; SPF 30 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Survival of motor neuron-related-splicing factor 30 [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SURVIVAL OF MOTOR NEURON-RELATED SPLICING FACTOR 30 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Survival of motor neuron-related-splicing factor 30; AltName: Full=SMN-related protein; AltName: Full=30 kDa splicing factor SMNrp; AltName: Full=Survival motor neuron domain-containing protein 1 [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=SMNDC1 Survival of motor neuron-related-splicing factor 30 [human-ipi-250309-contam.fasta]
  • IPI:IPI00025176.1|SWISS-PROT:O75940|TREMBL:B2RA27|ENSEMBL:ENSP00000358605;ENSP00000358616|REFSEQ:NP_005862|H-INV:HIT000035196|VEGA:OTTHUMP00000020474;OTTHUMP00000020475 Tax_Id=9606 Gene_Symbol=SMNDC1 Survival of motor neuron-related-splicing factor 30 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=SMNDC1 Survival of motor neuron-related-splicing factor 30 ENSG00000119953 IPI00025176 [drosphohumanreversed.fasta]
  • survival of motor neuron-related-splicing factor 30 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • O75940;Q5T3K6; RecName: Full=Survival of motor neuron-related-splicing factor 30; AltName: Full=SMN-related protein; AltName: Full=30 kDa splicing factor SMNrp; AltName: Full=Survival motor neuron domain-containing protein 1; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens GN=SMNDC1 [011711_HMR.fasta]
  • IPI:IPI00025176.1|SWISS-PROT:O75940|TREMBL:B2RA27;D3DRB1|ENSEMBL:ENSP00000358605;ENSP00000358616|REFSEQ:NP_005862|H-INV:HIT000035196|VEGA:OTTHUMP00000020474;OTTHUMP00000020475 Tax_Id=9606 Gene_Symbol=SMNDC1 Survival of motor neuron-related-splicing factor 30 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=SMNDC1 Synonyms=SMNR|SPF30 survival of motor neuron-related-splicing factor 30 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Survival of motor neuron-related-splicing factor 30 GN=SMNDC1 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 238 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEDLAKQLA SYKAQLQQVE AALSGNGENE DLLKLKKDLQ EVIELTKDLL STQPSETLAS  60
   61 SDSFASTQPT HSWKVGDKCM AVWSEDGQCY EAEIEEIDEE NGTAAITFAG YGNAEVTPLL 120
  121 NLKPVEEGRK AKEDSGNKPM SKKEMIAQQR EYKKKKALKK AQRIKELEQE REDQKVKWQQ 180
  181 FNNRAYSKNK KGQVKRSIFA SPESVTGKVG VGTCGIADKP MTQYQDTSKY NVRHLMPQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..238] PSI-BLAST 27.0 No description for 2hqeA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  3.08306835796752 bayes_pls_golite062009
  • binding
    		•  3.03932294945523 bayes_pls_golite062009
  • protein binding
    		•  2.81959915474598 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.39870293911569 bayes_pls_golite062009
  • DNA binding
    		•  2.20609628916256 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.54356011397295 bayes_pls_golite062009
  • transcription factor activity
    		•  1.48392797294737 bayes_pls_golite062009
  • transcription factor binding
    		•  1.47472377622426 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.30540808654443 bayes_pls_golite062009
  • chromatin binding
    		•  0.86899475761353 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  0.53946303154276 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.30405575160278 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  0.223495463070134 bayes_pls_golite062009
  • transcription activator activity
    		•  0.181941750923533 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.141502107934206 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  0.0975466265461999 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle