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View Structure Prediction Details

Protein: SMNDC1
Organism: Homo sapiens
Length: 238 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SMNDC1.

Description E-value Query
Range		 Subject
Range
gi|74214419 - gi|74214419|dbj|BAE40445.1| unnamed protein product [Mus musculus]
 3.0E-63 [1..238] [1..238]
SPF30_DANRE - Survival of motor neuron-related-splicing factor 30 OS=Danio rerio GN=smndc1 PE=2 SV=1
 2.0E-62 [1..238] [1..237]
gi|55732755 - gi|55732755|emb|CAH93075.1| hypothetical protein [Pongo abelii]
gi|73998555 - gi|73998555|ref|XP_535011.2| PREDICTED: similar to Survival of motor neuron-related splicing factor ...
SPF30_PONAB - Survival of motor neuron-related-splicing factor 30 OS=Pongo abelii GN=SMNDC1 PE=2 SV=1
gi|149689676 - gi|149689676|ref|XP_001496943.1| PREDICTED: similar to 30kDa splicing factor; SPF 30 [Equus caballus...
gi|114632789, gi... - gi|114632789|ref|XP_001142419.1| PREDICTED: hypothetical protein LOC450730 isoform 1 [Pan troglodyte...
gi|109090545 - gi|109090545|ref|XP_001085864.1| PREDICTED: survival motor neuron domain containing 1 [Macaca mulatt...
ENSCJAT00000036580 - null
 4.0E-61 [1..238] [1..238]
gi|50749781 - gi|50749781|ref|XP_421753.1| PREDICTED: similar to Survival of motor neuron-related splicing factor ...
 1.0E-60 [1..229] [299..527]
SPF30_BOVIN - Survival of motor neuron-related-splicing factor 30 OS=Bos taurus GN=SMNDC1 PE=2 SV=1
 1.0E-60 [1..238] [1..238]
SPF30_RAT - Survival of motor neuron-related-splicing factor 30 OS=Rattus norvegicus GN=Smndc1 PE=2 SV=1
 3.0E-60 [1..238] [1..238]
gi|55742438 - ref|NP_001006857.1| survival motor neuron domain containing 1 [Xenopus tropicalis]
SPF30_XENTR - Survival of motor neuron-related-splicing factor 30 OS=Xenopus tropicalis GN=smndc1 PE=2 SV=1
 1.0E-58 [1..238] [1..238]

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Predicted Domain #1
Region A:
Residues: [1-238] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEDLAKQLA SYKAQLQQVE AALSGNGENE DLLKLKKDLQ EVIELTKDLL STQPSETLAS  60
   61 SDSFASTQPT HSWKVGDKCM AVWSEDGQCY EAEIEEIDEE NGTAAITFAG YGNAEVTPLL 120
  121 NLKPVEEGRK AKEDSGNKPM SKKEMIAQQR EYKKKKALKK AQRIKELEQE REDQKVKWQQ 180
  181 FNNRAYSKNK KGQVKRSIFA SPESVTGKVG VGTCGIADKP MTQYQDTSKY NVRHLMPQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.0
Match: 2hqeA
Description: No description for 2hqeA was found.

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.08306835796752 bayes_pls_golite062009
binding 3.03932294945523 bayes_pls_golite062009
protein binding 2.81959915474598 bayes_pls_golite062009
nucleic acid binding 2.39870293911569 bayes_pls_golite062009
DNA binding 2.20609628916256 bayes_pls_golite062009
transcription repressor activity 1.54356011397295 bayes_pls_golite062009
transcription factor activity 1.48392797294737 bayes_pls_golite062009
transcription factor binding 1.47472377622426 bayes_pls_golite062009
transcription cofactor activity 1.30540808654443 bayes_pls_golite062009
chromatin binding 0.86899475761353 bayes_pls_golite062009
N-methyltransferase activity 0.53946303154276 bayes_pls_golite062009
transcription corepressor activity 0.30405575160278 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 0.223495463070134 bayes_pls_golite062009
transcription activator activity 0.181941750923533 bayes_pls_golite062009
sequence-specific DNA binding 0.141502107934206 bayes_pls_golite062009
histone methyltransferase activity 0.0975466265461999 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle