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Protein Overview: VPS60

General Information:
Name(s) found: VPS60 / YDR486C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Cytoplasmic and vacuolar membrane protein involved in late endosome to vacuole transport; required for normal filament maturation during pseudohyphal growth; may function in targeting cargo proteins for degradation; interacts with Vta1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 229 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    fungal-type vacuole membrane [IDALink to PubMed article]
    Biological Process: filamentous growth [IMPLink to PubMed article]
    response to drug [IMPLink to PubMed article]
    late endosome to vacuole transport [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRIFGYGNK KSHDQLLQES NQSMNQAQQS LSNRISQLDT QIAQLNFQLQ NIQKNLQRSN  60
   61 NKQPSLRKQA LKILNKRKQL ENMKDSLDSQ SWSMTQAQLT NDNLQNTMIT INALKQTNNA 120
  121 MKAQYGKINI DKLQDMQDEM LDLIEQGDEL QEVLAMNNNS GELDDISDAE LDAELDALAQ 180
  181 EDFTLPTSEN SLGNDMPSYL LGANAPPAFI DEEPNLDTED KNKALESAQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) VPS60 VTA1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data VPS60 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..229] Pfam 61.05061 No description for PF03357.7 was found. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle