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Protein Overview: HPA2

General Information:
Name(s) found: HPA2 / YPR193C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Tetrameric histone acetyltransferase with similarity to Gcn5p, Hat1p, Elp3p, and Hpa3p; acetylates histones H3 and H4 in vitro and exhibits autoacetylation activity [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 156 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: histone acetylation [NASLink to PubMed article]
    Molecular Function: histone acetyltransferase activity [IPILink to PubMed article][ISSLink to PubMed article][NASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNTSEDNIT VRFVTENDKE GWQRLWKSYQ DFYEVSFPDD LDDFNFGRFL DPNIKMWAAV  60
   61 AVESSSEKII GMINFFNHMT TWDFKDKIYI NDLYVDENSR VKGAGGKLIQ FVYDEADKLG 120
  121 TPSVYWCTDE SNHRAQLLYV KVGYKAPKIL YKRKGY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen STE50 HPA2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..156] PSI-BLAST 834.512579 Histone acetyltransferase HPA2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • N-acyltransferase activity
    		•  5.20638659012287 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  5.11115136755003 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  5.02728250402966 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  5.02728250402966 bayes_pls_golite062009
  • acetyltransferase activity
    		•  4.88581443210764 bayes_pls_golite062009
  • acyltransferase activity
    		•  4.72881921515185 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  4.70793039001114 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  4.69837915971204 bayes_pls_golite062009
  • transferase activity
    		•  2.87429355361226 bayes_pls_golite062009
    		• 2.58017351523387 bayes_pls_golite062009
  • catalytic activity
    		•  1.97933499002461 bayes_pls_golite062009
  • glycylpeptide N-tetradecanoyltransferase activity
    		•  0.952148883380044 bayes_pls_golite062009
  • myristoyltransferase activity
    		•  0.952148883380044 bayes_pls_golite062009
  • binding
    		•  0.437605892967756 bayes_pls_golite062009
  • protein binding
    		•  0.283213965640071 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle