Protein Overview: NCE102

General Information:
Name(s) found:	NCE102 / YPR149W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6325407\|ref\|NP_015475.1\| Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs); Nce102p [ [NCBI NR] gi\|45270936\|gb\|AAS56849.1\| YPR149W [Saccharomyces cerevisiae] [NCBI NR] gi\|2498617\|sp\|Q12207.1\|NCE2_YEAST RecName: Full=Non-classical export protein 2 [NCBI NR] pir\|\|S69036 NCE2 protein - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1508863\|gb\|AAB06618.1\| Nce2p [NCBI NR] gi\|1197842\|gb\|AAB05589.1\| Nce2p [NCBI NR] gi\|1066478\|gb\|AAB68287.1\| Nce2p [Saccharomyces cerevisiae] [NCBI NR] Non-classical export protein 2 OS=Saccharomyces cerevisiae GN=NCE102 PE=1 SV=1 [Swiss-Prot] NCE102 Protein involved in non-classical protein export pathway [mips] Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs) [SGD] (Q12207) Non-classical export protein 2 [4932.FASTACCERV.txt] Chr XVI from 829912-830433 [hmr_yeast5_DM3-1_pombe.fasta] Chr XVI from 829913-830434 [yeastorf3.fasta] NCE102, Chr XVI from 829913-830434 [yeast_orfs2] NCE102 SGDID:S0006353, Chr XVI from 829912-830433, Verified ORF [yeastflysequest.fasta] NCE102 SGDID:S0006353, Chr XVI from 829914-830435, Verified ORF [10112005cervSGD.fasta] Nce102p [Saccharomyces cerevisiae]gi\|1066478\|gb\|AAB68287.1\| Nce2p [Saccharomyces cerevisiae]gi\|45270936\|gb\|AAS56849.1\| YPR149W [Saccharomyces cerevisiae]gi\|2132360\|pir\|\|S69036 NCE2 protein - yeast (Saccharomyces cerevisiae)gi\|1508863\|gb\|AAB06618.1\| Nc [nrdb_11152004_Chlamydomonas] NCE102 SGDID:S000006353, Chr XVI from 829914-830435, Verified ORF, "Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycoli [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YPR149W [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Nce2p [nr-271106-contam.fasta] Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs); Nce102p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Non-classical export protein 2 [nr-271106-contam.fasta] Nce2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] NCE102 SGDID:S000006353, Chr XVI from 829914-830435, Verified ORF, "Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs)" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Non-classical export protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NCE102 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] NCE102 SGDID:S000006353, Chr XVI from 829918-830439, Genome Release 64-1-1, Verified ORF, "Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs)" [yeast-030211-contam.fasta] NCE102 SGDID:S000006353, Chr XVI from 829918-830439, Genome Release 64-2-1, Verified ORF, "Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs); NCE102 has a paralog, FHN1, that arose from the whole genome duplication" [20141208_orf_trans.fasta] TR7370\|c0_g1_i1\|g.5169 ORF TR7370\|c0_g1_i1\|g.5169 TR7370\|c0_g1_i1\|m.5169 type:complete len:174 (+) TR7370\|c0_g1_i1:229-750(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] TR4752\|c0_g1_i1\|g.3152 ORF TR4752\|c0_g1_i1\|g.3152 TR4752\|c0_g1_i1\|m.3152 type:complete len:174 (+) TR4752\|c0_g1_i1:318-839(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] TR4752\|c0_g2_i1\|g.3153 ORF TR4752\|c0_g2_i1\|g.3153 TR4752\|c0_g2_i1\|m.3153 type:complete len:174 (+) TR4752\|c0_g2_i1:318-839(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] YPR149W SGDID:S000006353, Chr XVI from 829918-830439, Genome Release 64-1-1, Verified ORF, "Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs)" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_3721\|g.2272 ORF asmbl_3721\|g.2272 asmbl_3721\|m.2272 type:complete len:174 (+) asmbl_3721:317-838(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta] asmbl_3105\|g.2695 ORF asmbl_3105\|g.2695 asmbl_3105\|m.2695 type:complete len:174 (+) asmbl_3105:207-728(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_3321\|g.2276 ORF ID=asmbl_3321\|g.2276 ID=asmbl_3321\|m.2276 type:complete len:174 (+) ID=asmbl_3321:317-838(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta] ID=asmbl_3105\|g.1894 ORF ID=asmbl_3105\|g.1894 ID=asmbl_3105\|m.1894 type:complete len:174 (+) ID=asmbl_3105:207-728(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	173 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA] mitochondrion [IDA ] integral to membrane [ISS] endoplasmic reticulum [IDA] plasma membrane [IDA]
Biological Process:	protein secretion [IGI][IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLALADNILR IINFLFLVIS IGLISSLLNT QHRHSSRVNY CMFACAYGIF TDSLYGVFAN  60
   61 FIEPLAWPLV LFTLDFLNFV FTFTAGTVLA VGIRAHSCNN SSYVDSNKIT QGSGTRCRQA 120
  121 QAAVAFLYFS CAIFLAKTLM SVFNMISNGA FGSGSFSKRR RTGQVGVPTI SQV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	LST8	No Comments	Reinke A, et al. (2004)
View Run	TOR2	No Comments	Reinke A, et al. (2004)
View Run	DAD1	Dam1-765 complex purified from yeast with Dad1-TAP	Shimogawa MM, et al. (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	RGD2	NCE102	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	NCE102	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..173]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2