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Protein Overview: AGC1

General Information:
Name(s) found: AGC1 / YPR021C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Mitochondrial amino acid transporter, acts both as a glutamate uniporter and as an aspartate-glutamate exchanger; involved in nitrogen metabolism and nitrogen compound biosynthesis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 902 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial inner membrane [ISSLink to PubMed article]
    Biological Process: L-glutamate transport [IDALink to PubMed article]
    aspartate transport [IDALink to PubMed article]
    Molecular Function: L-aspartate transmembrane transporter activity [IDALink to PubMed article]
    L-glutamate transmembrane transporter activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQINSNSRK KKQQLEVFKY FASVLTKEDK PISISNGMLD MPTVNSSKLT AGNGKPDTEK  60
   61 LTGELILTYD DFIELISSSK TIYSKFTDHS FNLNQIPKNV FGCIFFAIDE QNKGYLTLND 120
  121 WFYFNNLLEY DNYHLIILYE FFRKFDVENL KAKQKKELGS SSFNLKAADD RIKSINYGNR 180
  181 FLSFDDLLLN LNQFKDTIRL LHESIDDNFV KDNKLLLDWN DFRFLKFYKC YHENEEYLSL 240
  241 NSLVTILQND LKNEKIFIGF DRLAQMDSQG HRLALSKNQL TYLLRLFYSH RVSADIFSSL 300
  301 NLSNTELLKA DNNSIPYNVF KDIFYLFQNF DLLNQIFHKY VTENNLNEQD IREQIVTKND 360
  361 FMTVLNAQYN KVNNIIEFSP SQINLLFSIV ANSKENRRLR KRNQDRDDEL LNDHHYDSDI 420
  421 DFFIHNEYLH GVSRSRKNLE SFNDYYHDLS DGFDQDSGVK KASKASTGLF ESVFGGKKDK 480
  481 ATMRSDLTIE DFMKILNPNY LNDLVHQMEL QKNQNESLYI NYYFYPIFDS LYNFSLGSIA 540
  541 GCIGATVVYP IDFIKTRMQA QRSLAQYKNS IDCLLKIISR EGIKGLYSGL GPQLIGVAPE 600
  601 KAIKLTVNDF MRNRLTDKNG KLSLFPEIIS GASAGACQVI FTNPLEIVKI RLQVQSDYVG 660
  661 ENIQQANETA TQIVKKLGLR GLYNGVAACL MRDVPFSAIY FPTYAHLKKD LFDFDPNDKT 720
  721 KRNRLKTWEL LTAGAIAGMP AAFLTTPFDV IKTRLQIDPR KGETKYNGIF HAIRTILKEE 780
  781 SFRSFFKGGG ARVLRSSPQF GFTLAAYELF KGFIPSPDNK LKSREGRKRF CIDDDAGNEE 840
  841 TVVHSNGELP QQKFYSDDRK HANYYYKSCQ IAKTFIDLDN NFSRFDSSVY KNFQEHLRSI 900
  901 NG

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) AGC1 SFC1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run BIR1 sample bir 1 from feb 2005 Sandall S, et all (2006)
    View Run MLP2 #20 Asynchronous Prep1-TiO2 Phosphopeptide enrichment, PartB Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..170] FFAS03 2.81 NMR SOLUTION STRUCTURE OF CALERYTHRIN, AN EF-HAND CALCIUM-BINDING PROTEIN
    2 View Details [171..348] PSI-BLAST 4.522879 Calmodulin
    3 View Details [349..521] deduced N/A No confident structure predictions are available.
    4 View Details [522..818] PSI-BLAST 108.0 structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside
    5 View Details [819..902] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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