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Protein Overview: HAL1

General Information:
Name(s) found: HAL1 / YPR005C [SGD]
Description(s) found:
Found 30 descriptions.
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  • Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux; expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 294 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: response to salt stress [IGILink to PubMed article][IMPLink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHFKDLGLHD YTLKNLMYEN NCCKFYDAVD ENNISYVLKF VPSDVTSEGD TFPFVDRFQV  60
   61 KEGVFLVYSS NDFGKEGTDY FTYTGSGGNE VHISGTSSEA GIKPQFIETC HPKHLKRGTK 120
  121 EQEDINSSTS KKSAVINNFS GEKTPNPRPQ SSNISERETY VGILNVKCKN KNSSKIRSEK 180
  181 LVSSVIETKH TPGLASILSK EGTTYPNNAD GKHISIVNPS SKIYHSSHKQ IVKTPIPKSG 240
  241 LSPIERCPFN GQNIKCYSPR PLDHESPQRD FNNNFQLRIL KSSVLQRRQS TQNS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..294] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle