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Protein Overview: RMI1

General Information:
Name(s) found: RMI1 / YPL024W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex; stimulates superhelical relaxing and ssDNA binding activities of Top3p; involved in response to DNA damage; null mutants display increased rates of recombination and delayed S phase [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 241 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    RecQ helicase-Topo III complex [IDALink to PubMed article][IPILink to PubMed article]
    Biological Process: response to DNA damage stimulus [IGILink to PubMed article]
    Molecular Function: four-way junction DNA binding [IDALink to PubMed article]
    single-stranded DNA binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFSSILSQD ITDDITPPAY SATLGSREQI VFRAYQNEPW LAGTASNLIL DKKLVIVDRE  60
   61 LLFQVLMVEN ITKSKLTQID DIKTKLDPKK QKVDRLRSGA QGNGAKKYEV ITQVDMEDDG 120
  121 NVADNNCAKE NNSNNNSSAA KNKAVFKLTL QSKSGDVFFA INSTPISWSS CMLGSKIVIL 180
  181 PGTVFNRGVF ILKDSQVIFL GGINRVWNEN RDQKFCDYLE SKLQRDKQLV NGGSKKRKAN 240
  241 D

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RMI1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..241] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle