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Protein Overview: PUT4

General Information:
Name(s) found: PUT4 / YOR348C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Proline permease, required for high-affinity transport of proline; also transports the toxic proline analog azetidine-2-carboxylate (AzC); PUT4 transcription is repressed in ammonia-grown cells [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 627 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [ISSLink to PubMed article]
    Biological Process: neutral amino acid transport [IDALink to PubMed article]
    proline catabolic process [TASLink to PubMed article]
    Molecular Function: neutral amino acid transmembrane transporter activity [IDALink to PubMed article]
    epsilon hydroxylase activity [IGILink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNILPFHKN NRHSAGVVTC ADDVSGDGSG GDTKKEEDVV QVTESPSSGS RNNHRSDNEK  60
   61 DDAIRMEKIS KNQSASSNGT IREDLIMDVD LEKSPSVDGD SEPHKLKQGL QSRHVQLIAL 120
  121 GGAIGTGLLV GTSSTLHTCG PAGLFISYII ISAVIYPIMC ALGEMVCFLP GDGSDSAGST 180
  181 ANLVTRYVDP SLGFATGWNY FYCYVILVAA ECTAASGVVE YWTTAVPKGV WITIFLCVVV 240
  241 ILNFSAVKVY GESEFWFASI KILCIVGLII LSFILFWGGG PNHDRLGFRY WQHPGAFAHH 300
  301 LTGGSLGNFT DIYTGIIKGA FAFILGPELV CMTSAECADQ RRNIAKASRR FVWRLIFFYV 360
  361 LGTLAISVIV PYNDPTLVNA LAQGKPGAGS SPFVIGIQNA GIKVLPHIIN GCILTSAWSA 420
  421 ANAFMFASTR SLLTMAQTGQ APKCLGRINK WGVPYVAVGV SFLCSCLAYL NVSSSTADVF 480
  481 NWFSNISTIS GFLGWMCGCI AYLRFRKAIF YNGLYDRLPF KTWGQPYTVW FSLIVIGIIT 540
  541 ITNGYAIFIP KYWRVADFIA AYITLPIFLV LWFGHKLYTR TWRQWWLPVS EIDVTTGLVE 600
  601 IEEKSREIEE MRLPPTGFKD KFLDALL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) AGP3 GAP1 PUT4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data

    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..93] deduced N/A No confident structure predictions are available.
    2 View Details [94..295] MSA 7.104995 View MSA. No confident structure predictions are available.
    3 View Details [296..432] MSA 2.131995 View MSA. No confident structure predictions are available.
    4 View Details [433..627] MSA 4.111996 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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