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Protein Overview: SIA1

General Information:
Name(s) found: SIA1 / YOR137C [SGD]
Description(s) found:
Found 30 descriptions.
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  • Protein of unassigned function involved in activation of the Pma1p plasma membrane H+-ATPase by glucose [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 622 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: proton transport [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLHYRRRFN FLRRILFILC ITSLYLSRDS LKLHAKNVLM DHNVAEYHGG MIDDIQILRC  60
   61 YHWYRQCSSL YAPKLHPSNT AKKIKDKNSI LWTRVSKNIT VETLYSLQSG PFYNSYLYVH 120
  121 LKDFQSNPKN TIKELAIARD SALIPLQVLR DINKLVKSSD SSVFHNHVYL REKPTSSWWK 180
  181 LLFGISVDTD NIAVFGEEWV YKGSGIWCKY ILNDDDNDAP ITNLEIYLGS SFIESRPSWK 240
  241 EVIHEFHRNN IPSLPISITR KLETKNHHHK FSNGLLGSLR TPSKDINIQV DADYKITSPH 300
  301 IQFSRGQRSF KILQITDFHF KCTDNSMTVI NEIKTVNFID RVLASENPDL VVITGDLLDS 360
  361 HNTIDYQTCI MKVVQPMISN KIPYAISLGV SDESNLATSA QIRDFIRNLP YTFNNVASEE 420
  421 GHMAIEVSFK KKLTKNTLLE RDIDTEDETN PSEALFFVFD SFAPVNNFLQ DYNDLIGKID 480
  481 FGLAFQYFPL SEYRPHGLFP IIGQYNERST LTVDTPRSRG QVSMTINGKH YKSFLDILSL 540
  541 WNIKGVSCGH EHNNDCCLQS KNEMWLCYGG SAGIGLPRIQ GIYPTVRLFN LDDILDEITS 600
  601 WKRNSNLVDE VYDYQYIYKG KQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CRP1 IDS2 PDR1 PEP4 PRC1 RTN1 SIA1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run TAM41 No Comments Hazbun TR, et al. (2003)
    View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..281] deduced N/A No confident structure predictions are available.
    2 View Details [282..622] PSI-BLAST 41.30103 Mammalian purple acid phosphatase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • hydrolase activity
    		•  1.61379532420857 bayes_pls_golite062009
  • catalytic activity
    		•  0.632097679642303 bayes_pls_golite062009
  • binding
    		•  0.0938060766019471 bayes_pls_golite062009
  • phosphoprotein phosphatase activity
    		•  0.0412556599175502 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.0266041407862333 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.0182359198166776 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle