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Protein Overview: CRC1

General Information:
Name(s) found: CRC1 / YOR100C [SGD]
Description(s) found:
Found 32 descriptions.
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  • Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 327 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    mitochondrial inner membrane [IDALink to PubMed article]
    Biological Process: fatty acid metabolic process [IDALink to PubMed article]
    Molecular Function: carnitine:acyl carnitine antiporter activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDTSLSES SLLKEESGSL TKSRPPIKSN PVRENIKSFV AGGVGGVCAV FTGHPFDLIK  60
   61 VRCQNGQANS TVHAITNIIK EAKTQVKGTL FTNSVKGFYK GVIPPLLGVT PIFAVSFWGY 120
  121 DVGKKLVTFN NKQGGSNELT MGQMAAAGFI SAIPTTLVTA PTERVKVVLQ TSSKGSFIQA 180
  181 AKTIVKEGGI ASLFKGSLAT LARDGPGSAL YFASYEISKN YLNSRQPRQD AGKDEPVNIL 240
  241 NVCLAGGIAG MSMWLAVFPI DTIKTKLQAS STRQNMLSAT KEIYLQRGGI KGFFPGLGPA 300
  301 LLRSFPANAA TFLGVEMTHS LFKKYGI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CRC1 PMT5 RUB1 RUD3
    View Details Ho Y, et al. (2002) CRC1 MSI1 RLF2 SNU66

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..327] ORFEUS 7.76 Peroxisomal acyl-CoA oxidase-II, domains 3 and 4; Peroxisomal acyl-CoA oxidase-II, domains 1 and 2


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle